Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.52 |
| ▸ | DGKA | P23743 | 1/20 | 0.67 |
| ▸ | PAM | P19021 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | PPARD | Q03181 | 4/20 | 0.52 |
| ▸ | PPARA | Q07869 | 4/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6448229 | 1.00 | DGKA (0.67) | DGKAPAMTSHRMAPTCYP1A2 | |
| Acetic Acid SCHEMBL5395399 | 1.00 | DGKA (0.67) | DGKAPAMTSHRMAPTCYP1A2 | |
| Ethyl Tetradecanoate SCHEMBL8330964 | 1.00 | DGKA (0.67) | DGKAPAMTSHRMAPTCYP1A2 | |
| Acetic Acid SCHEMBL1682182 | 1.00 | DGKA (0.67) | DGKAPAMTSHRMAPTCYP1A2 | |
| Acetic Acid SCHEMBL173634 | 1.00 | DGKA (0.67) | DGKAPAMTSHRMAPTCYP1A2 | |
| Acetic Acid SCHEMBL2213929 | 1.00 | DGKA (0.67) | DGKAPAMTSHRMAPTCYP1A2 | |
| Acetic Acid SCHEMBL787652 | 1.00 | DGKA (0.67) | DGKAPAMTSHRMAPTCYP1A2 | |
| Acetic Acid SCHEMBL3028566 | 1.00 | DGKA (0.67) | DGKAPAMTSHRMAPTCYP1A2 | |
| Acetic Acid SCHEMBL543614 | 1.00 | DGKA (0.67) | DGKAPAMTSHRMAPTCYP1A2 | |
| Acetic Acid SCHEMBL8469053 | 1.00 | DGKA (0.67) | DGKAPAMTSHRMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515956-B | Benzimidazole derivative, and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-118126046-A | Substituted macrocyclic compound, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-06-04 | — | — | CN | disclosed |
| US-20240166627-A1 | Terpyridinedione compound or salt thereof, and preparation method and application thereof | SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) | 2024-05-23 | — | — | US | disclosed |
| CN-116648244-B | Terpyridyl dione compound or salt thereof, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-116648244-A | Terpyridyl dione compound or salt thereof, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-08-25 | — | — | CN | disclosed |
| EP-3559007-B1 | SULFONAMIDE COMPOUNDS HAVING TNAP INHIBITORY ACTIVITY | DAIICHI SANKYO CO LTD (JP) | 2023-08-16 | — | — | EP | disclosed |
| EP-4219463-A1 | TERPYRIDINE DIKETONE COMPOUND OR SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |
| WO-2023121378-A1 | (S)-2-(2-METHYLAZETIDIN-1-YL)PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 엘지화학 | 2023-06-29 | — | — | WO | disclosed |
| US-11655235-B2 | Pyrrolidine and piperidine compounds | YUHAN CORPORATION (KR) | 2023-05-23 | — | — | US | disclosed |
| US-5028416-A | Moisturizers, cosmetics, amide or amine containing hydroxy groups and alkyl ether groups | KAO CORPORATION (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0433759-A1 | 4-Substituted alkyl carbapenem antibiotics | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | disclosed |
| US-4985547-A | Containing an Amide Derivative | KAO CORPORATION (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0396065-A1 | Novel amino acid derivatives possessing renin-inhibitory activities | Japan Tobacco Inc. (JP) | 1990-11-07 | — | — | EP | disclosed |
| US-4918170-A | Process for producing gangliosides | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| US-4914035-A | REACTING ALKYLTHIOSIALIC ACID DERIVATIVE WITH HYDROXY COMPOUND AT LOW TEMPERATURE IN POLAR SOLVENT WITH THIOPHILIC PROMOTER | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4826820-A | BACTERICIDES | BEECHAM GROUP P.L.C. (GB) | 1989-05-02 | — | — | US | disclosed |
| EP-0282816-A2 | External skin care preparation | Kao Corporation (JP) | 1988-09-21 | — | — | EP | disclosed |
| EP-0216169-A2 | Erythromycin derivatives | BEECHAM GROUP PLC (GB) | 1987-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166627-A1 | Terpyridinedione compound or salt thereof, and preparation method and application thereof | TNF, MAPKAPK2, MAPK1 | ESR1 4818/4885DGKA 1698/4885PAM 3131/4885 |
| US-11655235-B2 | Pyrrolidine and piperidine compounds | FAP, APC, VHL | ESR1 4473/4885DGKA 4255/4885PAM 1777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.