Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.64 |
| ▸ | CA2 | P00918 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.64 |
| ▸ | TTR | P02766 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | DHFR | P00374 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | ALB | P02768 | 1/20 | 0.64 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.64 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 4/20 | 0.55 |
| ▸ | CA7 | P43166 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10888678 | 0.90 | ACMSD (0.61) | CA1CA2KDM4EALDH1A1HPGD | |
| SCHEMBL410760 | 0.85 | CA1 (0.69) | CA1CA2KDM4EALDH1A1HPGD | |
| SCHEMBL3807219 | 0.85 | ACMSD (0.55) | CA1CA2KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL15392057 | 0.85 | ACMSD (0.55) | CA1CA2KDM4EALDH1A1HPGD | |
| SCHEMBL12608936 | 0.83 | ACMSD (0.75) | CA1CA2KDM4EALDH1A1HPGD | |
| SCHEMBL10783826 | 0.83 | CA1 (0.53) | CA1CA2KDM4EALDH1A1HPGD | |
| SCHEMBL21562586 | 0.82 | ACMSD (0.69) | CA1CA2KDM4EALDH1A1HPGD | |
| Acetic Acid SCHEMBL28030195 | 0.82 | ACMSD (0.55) | CA1CA2KDM4EALDH1A1HPGD | |
| SCHEMBL1818476 | 0.82 | CA1 (0.64) | CA1CA2KDM4EALDH1A1HPGD | |
| SCHEMBL9893460 | 0.82 | ACMSD (0.64) | CA1CA2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150025006-A1 | Pharmaceutical Combinations Including Anti-Inflammatory and Antioxidant Conjugates Useful for Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2015-01-22 | — | — | US | disclosed |
| EP-2755645-A1 | PHARMACEUTICAL COMBINATIONS INCLUDING ANTI-INFLAMMATORY AND ANTIOXIDANT CONJUGATES USEFUL FOR TREATING METABOLIC DISORDERS | Genmedica Therapeutics SL (ES) | 2014-07-23 | — | — | EP | disclosed |
| US-20130267726-A1 | Thiocarbonates as Anti-Inflammatory and Antioxidant Compounds Useful For Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2013-10-10 | — | — | US | disclosed |
| US-8466197-B2 | Thiocarbonates as anti-inflammatory and antioxidant compounds useful for treating metabolic disorders | GENMEDICA THERAPEUTICS SL (ES) | 2013-06-18 | — | — | US | disclosed |
| WO-2013037985-A1 | PHARMACEUTICAL COMBINATIONS INCLUDING ANTI-INFLAMMATORY AND ANTIOXIDANT CONJUGATES USEFUL FOR TREATING METABOLIC DISORDERS | GENMEDICA THERAPUTICS SL (ES) | 2013-03-21 | — | — | WO | disclosed |
| WO-2012080371-A1 | NEW THIOCARBONATES AS ANTI-INFLAMMATORY AND ANTIOXIDANT COMPOUNDS USEFUL FOR TREATING METABOLIC DISORDERS | GENMEDICA THERAPEUTICS SL (ES) | 2012-06-21 | — | — | WO | disclosed |
| US-20120149769-A1 | Thiocarbonates as Anti-Inflammatory and Antioxidant Compounds Useful For Treating Metabolic Disorders | GENMEDICA THERAPEUTICS SL (ES) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267726-A1 | Thiocarbonates as Anti-Inflammatory and Antioxidant Compounds Useful For Treating Metabolic Disorders | CPT1B, LTC4S, TXNRD2 | CA1 4299/4885CA2 2726/4885KDM4E 4746/4885 |
| US-20120149769-A1 | Thiocarbonates as Anti-Inflammatory and Antioxidant Compounds Useful For Treating Metabolic Disorders | CPT1B, LTC4S, TXNRD2 | CA1 4299/4885CA2 2726/4885KDM4E 4746/4885 |
| US-20150025006-A1 | Pharmaceutical Combinations Including Anti-Inflammatory and Antioxidant Conjugates Useful for Treating Metabolic Disorders | IAPP, AMY2A, GPR119 | CA1 1993/4885CA2 1148/4885KDM4E 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.