Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1274623 | 0.95 | S1PR1 (0.34) | S1PR1S1PR2S1PR4S1PR5CHRNA7 | |
| SCHEMBL1275826 | 0.85 | KDM4E (0.40) | TRPV1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL1274944 | 0.84 | HDAC3 (0.40) | S1PR1S1PR2S1PR4S1PR5KLKB1 | |
| SCHEMBL9894275 | 0.82 | BACE1 (0.40) | LMNACYP1A2CYP3A4 | |
| SCHEMBL9895253 | 0.82 | S1PR4 (0.39) | S1PR1S1PR2S1PR4S1PR5CHRNA7 | |
| SCHEMBL1274575 | 0.81 | LOXL2 (0.44) | S1PR1S1PR2S1PR4S1PR5KLKB1 | |
| SCHEMBL1274558 | 0.80 | MAP3K5 (0.36) | HIF1AEPAS1MAPTTRPV1KDM4E | |
| SCHEMBL1274338 | 0.80 | ALDH1A1 (0.39) | S1PR1S1PR2S1PR4S1PR5KLKB1 | |
| SCHEMBL1274590 | 0.79 | S1PR1 (0.35) | S1PR1S1PR2S1PR4S1PR5CHRNA7 | |
| SCHEMBL1274328 | 0.78 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153497-A2 | PESTICIDAL CARBOXAMIDES | Bayer Cropscience AG (DE) | 2017-04-12 | — | — | EP | disclosed |
| US-9227923-B2 | Pesticidal carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-05 | — | — | US | disclosed |
| US-20120149910-A1 | Pesticidal Carboxamides | BAYER CROPSCIENCE AG (DE) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149910-A1 | Pesticidal Carboxamides | DDT, ACHE, AADAC | S1PR1 2164/4885S1PR2 1659/4885S1PR4 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.