SCHEMBL9895253

SCHEMBL9895253

CCc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1ccc(CN)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 3/20 0.39
S1PR2 O95136 1/20 0.39
S1PR1 P21453 1/20 0.39
S1PR5 Q9H228 1/20 0.39
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
KLK1 P06870 4/20 0.37
USP28 Q96RU2 3/20 0.37
CHRNA7 P36544 1/20 0.37
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
CSNK2A1 P68400 1/20 0.36
CSNK2A3 Q8NEV1 1/20 0.36
KLKB1 P03952 3/20 0.36
PLG P00747 2/20 0.36
KLK6 Q92876 2/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
MAPT P10636 2/20 0.36
TP53 P04637 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1274575 0.88 LOXL2 (0.44) S1PR4S1PR2S1PR1S1PR5KLK1
SCHEMBL1274944 0.84 HDAC3 (0.40) S1PR4S1PR2S1PR1S1PR5HPGD
SCHEMBL1275429 0.82 FLT1 (0.43) HPGDSMN1; SMN2MAPTTP53RAB9A
SCHEMBL9895140 0.82 S1PR1 (0.36) S1PR4S1PR2S1PR1S1PR5ALOX15
SCHEMBL9894640 0.81 HTT (0.38) HPGDALOX15KLK1KLKB1PLG
SCHEMBL9894521 0.80 LOXL2 (0.48) S1PR4S1PR2S1PR1S1PR5KLK1
SCHEMBL1275566 0.80 MAPT (0.41) HPGDALOX15MAPTRAB9AALDH1A1
SCHEMBL9895607 0.80 DHODH (0.34) HPGDKLKB1SMN1; SMN2TP53LMNA
SCHEMBL1274909 0.79 KCNJ11 (0.38) S1PR1SMN1; SMN2MAPTTP53MEN1
SCHEMBL1274338 0.79 ALDH1A1 (0.39) S1PR4S1PR2S1PR1S1PR5HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3153497-A2 PESTICIDAL CARBOXAMIDES Bayer Cropscience AG (DE) 2017-04-12 EP disclosed
US-9227923-B2 Pesticidal carboxamides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-01-05 US disclosed
US-20120149910-A1 Pesticidal Carboxamides BAYER CROPSCIENCE AG (DE) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149910-A1 Pesticidal Carboxamides DDT, ACHE, AADAC S1PR4 2004/4885S1PR2 1659/4885S1PR1 2164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.