Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921677 | 0.81 | MCL1 (0.40) | MTNR1AMTNR1BRXRARXRBALDH1A1 | |
| SCHEMBL24791847 | 0.80 | MTNR1A (0.46) | MTNR1AMTNR1BRXRARXRBNQO2 | |
| SCHEMBL9926560 | 0.79 | MTNR1A (0.44) | MTNR1AMTNR1BRXRARXRBALDH1A1 | |
| SCHEMBL2254145 | 0.79 | MTNR1A (0.48) | MTNR1AMTNR1BRXRARXRBALDH1A1 | |
| SCHEMBL1495870 | 0.75 | MTNR1A (0.44) | MTNR1AMTNR1BALDH1A1KDM4ENR1H4 | |
| SCHEMBL12318344 | 0.74 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1L3MBTL1KMT2A | |
| Nitrogen SCHEMBL28021202 | 0.72 | MTNR1A (0.46) | MTNR1AMTNR1BALDH1A1L3MBTL1KMT2A | |
| SCHEMBL20565266 | 0.72 | MTNR1A (0.41) | MTNR1AMTNR1BALDH1A1L3MBTL1BRD4 | |
| SCHEMBL29536890 | 0.72 | MTNR1A (0.41) | MTNR1AMTNR1BALDH1A1L3MBTL1BRD4 | |
| SCHEMBL12164519 | 0.71 | ALDH1A1 (0.42) | ALDH1A1POLBMCL1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | BROTHERTON-PLEISS CHRISTINE E (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | P2RX7, P2RX3, P2RX2 | MTNR1A 316/4885MTNR1B 259/4885RXRA 263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.