Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Fosfomycin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fosfomycin SCHEMBL20597494 | 1.00 | LMNA (0.48) | — | |
| Fosfomycin SCHEMBL3499425 | 0.97 | LMNA (0.46) | — | |
| Fosfomycin SCHEMBL3168929 | 0.97 | — | — | |
| Fosfomycin SCHEMBL8633252 | 0.97 | — | — | |
| Fosfomycin SCHEMBL9634477 | 0.97 | — | — | |
| Fosfomycin SCHEMBL5595663 | 0.97 | LMNA (0.50) | — | |
| Fosfomycin SCHEMBL989825 | 0.97 | — | — | |
| Fosfomycin SCHEMBL3168937 | 0.97 | — | — | |
| Fosfomycin SCHEMBL10492648 | 0.97 | — | — | |
| Fosfomycin SCHEMBL50951 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12274830-B2 | Nitric oxide inhalation therapy for infants with bronchiolitis | BEYOND AIR LTD (IL) | 2025-04-15 | — | — | US | claimed |
| CN-113336791-B | Production method of fosfomycin calcium bulk drug | 千辉药业（安徽）有限责任公司 | 2024-12-24 | — | — | CN | claimed |
| CN-221992314-U | Fosfomycin calcium drying device | 湖北迅达药业股份有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-118389556-A | Perforin preparation method and application thereof | 复旦大学附属中山医院 | 2024-07-26 | — | — | CN | claimed |
| US-20240173512-A1 | METHODS FOR POTENTIATING ANTIMICROBIAL AGENTS | STREETERVILLE CAPITAL, LLC | 2024-05-30 | — | — | US | claimed |
| US-11890421-B2 | Methods for potentiating antimicrobial agents | BEYOND AIR LTD (IL) | 2024-02-06 | — | — | US | claimed |
| EP-4268805-A1 | FOSFOMYCIN FORMULATION FOR PARENTERAL ADMINISTRATION AND METHOD OF MANUFACTURING SAME | Georgopoulos, Apostolos (AT) | 2023-11-01 | — | — | EP | claimed |
| CN-116570763-A | Enzyme-loaded calcium-phosphorus modified polyurethane bioactive material and preparation method thereof | 四川大学 | 2023-08-11 | — | — | CN | claimed |
| US-20220218792-A1 | COMPOSITIONS TO PROMOTE THE HEALING OF SKIN ULCERS AND WOUNDS | Reponex Pharmaceuticals A/S (DK) | 2022-07-14 | — | — | US | claimed |
| CN-113336791-A | Production method of fosfomycin calcium bulk drug | 千辉药业（安徽）有限责任公司 | 2021-09-03 | — | — | CN | claimed |
| WO-2015118069-A1 | COMPOSITIONS TO PROMOTE THE HEALING OF SKIN ULCERS AND WOUNDS | Reponex Pharmaceuticals Aps (DK) | 2015-08-13 | — | — | WO | claimed |
| CN-104546767-A | Fosfomycin calcium composition freeze-dried tablet and preparation method thereof | HAINAN WEKON PHARMACEUTICAL QIANSHAN CO LTD | 2015-04-29 | — | — | CN | claimed |
| US-20140134253-A1 | DRY POWDER FOSFOMYCIN/TOBRAMYCIN FORMULATION FOR INHALATION | GILEAD SCIENCES, INC. (US) | 2014-05-15 | — | — | US | claimed |
| WO-2013112548-A1 | GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-08-01 | — | — | WO | claimed |
| WO-2012154483-A1 | DRY POWDER FOSFOMYCIN/TOBRAMYCIN FORMULATION FOR INHALATION | GILEAD SCIENCES, INC. (US) | 2012-11-15 | — | — | WO | claimed |
| WO-2009131692-A1 | SUBSTRATES FOR DELIVERY OF PHYSIOLOGICALLY ACTIVE AGENTS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2009-10-29 | — | — | WO | claimed |
| CN-1757393-A | Fosfocina calcium disperser, and its prepn. method | WANG WANGYU (CN) | 2006-04-12 | — | — | CN | claimed |
| CN-1160077-C | Exterior-applied medicine containing phosphonomycin calcium and its application | 沈阳药科大学 | 2004-08-04 | — | — | CN | claimed |
| CN-1273824-A | Exterior-applied medicine containing phosphonomycin calcium and its application | UNIV SHENYANG PHARMACY (CN) | 2000-11-22 | — | — | CN | claimed |
| WO-2000000179-A1 | SOLID DISPERSED PREPARATION OF POORLY WATER-SOLUBLE DRUG CONTAINING OIL, FATTY ACID OR MIXTURES THEREOF | WON JIN BIOPHARMA CO., LTD. (KR) | 2000-01-06 | — | — | WO | claimed |