Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Fosfomycin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fosfomycin SCHEMBL3168937 | 1.00 | — | — | |
| Fosfomycin SCHEMBL3168929 | 1.00 | — | — | |
| Fosfomycin SCHEMBL9634477 | 1.00 | — | — | |
| Fosfomycin SCHEMBL10492648 | 1.00 | — | — | |
| Fosfomycin SCHEMBL989825 | 1.00 | — | — | |
| Fosfomycin SCHEMBL50951 | 1.00 | — | — | |
| Fosfomycin SCHEMBL5595663 | 1.00 | LMNA (0.50) | — | |
| Fosfomycin SCHEMBL989824 | 0.97 | — | — | |
| Fosfomycin SCHEMBL9634052 | 0.97 | LMNA (0.48) | — | |
| Fosfomycin SCHEMBL20597804 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678176-A1 | AMINO ACID SALTS OF FOSFOMYCIN AND COMPOSITIONS THEREOF | Ercros, S.A. (ES) | 2026-01-14 | — | — | EP | disclosed |
| US-5728572-A | Growth media for entomophthoralean hyphal bodies | GENESIS GROUP INC. (CA) | 1998-03-17 | — | — | US | disclosed |
| EP-0094815-B1 | OLIGOPEPTIDE PRODRUGS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-01-11 | — | — | EP | disclosed |
| US-4675315-A | SIDE EFFECT REDUCTION | LA COMPANIA ESPANOLA DE LA PENICILINA Y ANTIBIOTICOS, S.A. (ES) | 1987-06-23 | — | — | US | disclosed |
| EP-0161843-A1 | New salts of fosfomycin with imidazole | COMPANIA ESPANOLA DE LA PENICILINA Y ANTIBIOTICOS S.A. (ES) | 1985-11-21 | — | — | EP | disclosed |
| US-4479898-A | Oligopeptide prodrugs | SMITHKLINE BECKMAN CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4454065-A | INCREASE CELL MEMBRANE PERMEABILITY | SMITHKLINE BECKMAN CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |
| US-3943153-A | BACTERICIDES | MERCK & CO., INC. (US) | 1976-03-09 | — | — | US | disclosed |
| US-3935309-A | CHLORAMPHENICOL | MERCK & CO., INC. (US) | 1976-01-27 | — | — | US | disclosed |
| US-3914231-A | ({31 )(Cis-1,2-epoxypropyl)-phosphonic acid and salts thereof | MERCK & CO INC | 1975-10-21 | — | — | US | disclosed |