Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Fosfomycin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fosfomycin SCHEMBL3168937 | 1.00 | — | — | |
| Fosfomycin SCHEMBL3168929 | 1.00 | — | — | |
| Fosfomycin SCHEMBL8633252 | 1.00 | — | — | |
| Fosfomycin SCHEMBL9634477 | 1.00 | — | — | |
| Fosfomycin SCHEMBL10492648 | 1.00 | — | — | |
| Fosfomycin SCHEMBL989825 | 1.00 | — | — | |
| Fosfomycin SCHEMBL5595663 | 1.00 | LMNA (0.50) | — | |
| Fosfomycin SCHEMBL989824 | 0.97 | — | — | |
| Fosfomycin SCHEMBL9634052 | 0.97 | LMNA (0.48) | — | |
| Fosfomycin SCHEMBL20597804 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 21365 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026106551-A1 | ANTIMICROBIAL PEPTIDE NANONETS AND METHODS OF USE THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2026-05-21 | — | — | WO | claimed |
| EP-4743153-A1 | MEDICAL SYSTEMS FOR TREATING CONDITIONS AND DISEASES OF THE PATIENT'S BODY CAVITIES | UTT Urine Topical Treatment Ltd (IL) | 2026-05-20 | — | — | EP | claimed |
| CN-118304316-B | Application of cladribine in preparation of drug for inhibiting growth of multi-drug resistant klebsiella pneumoniae | 华南农业大学 | 2026-05-15 | — | — | CN | claimed |
| EP-4739326-A2 | PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA | SNIPR Biome ApS (DK) | 2026-05-13 | — | — | EP | claimed |
| CN-122012668-A | Preparation method and application of flat plate for detecting minimum inhibitory concentration of fosfomycin by simple agar dilution method | 温州市中医院 | 2026-05-12 | — | — | CN | claimed |
| US-20260124224-A1 | USE OF COMBINED COMPOSITION IN PREPARING DRUG FOR RESISTING FUNGAL AND BACTERIAL INFECTIONS | NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY (CN) | 2026-05-07 | — | — | US | claimed |
| EP-4736841-A1 | A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT | IQ medical GmbH (DE) | 2026-05-06 | — | — | EP | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-4734966-A2 | SYSTEM AND METHOD FOR SUSTAINED RELEASE OF AGENTS IN THE BLADDER | Watershed Medical, Inc. (US) | 2026-05-06 | — | — | EP | claimed |
| US-20260115234-A1 | PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA | SNIPR BIOME APS (DK) | 2026-04-30 | — | — | US | claimed |
| US-4560553-A | THERAPEUTIC, COSMETIC;MIXTURES OF HYPOTENSIVES, ANESTHETICS, BETA-BLOCKERS AND MICROBIOCIDES | MERCK & CO., INC. (US) | 1985-12-24 | — | — | US | claimed |
| EP-0161843-A1 | New salts of fosfomycin with imidazole | COMPANIA ESPANOLA DE LA PENICILINA Y ANTIBIOTICOS S.A. (ES) | 1985-11-21 | — | — | EP | claimed |
| EP-0036138-B1 | COMPOSITION OF MATTER FOR TOPICAL APPLICATION COMPRISING A BIO-AFFECTING AGENT AND N,N-DIETHYL-M-TOLUAMIDE | MERCK & CO. INC. (US) | 1985-08-28 | — | — | EP | claimed |
| US-4479947-A | Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group | MERCK & CO., INC. (US) | 1984-10-30 | — | — | US | claimed |
| EP-0070013-A1 | Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group | MERCK & CO. INC. (US) | 1983-01-19 | — | — | EP | claimed |
| EP-0027597-B1 | MONO(2-AMMONIUM-2-HYDROXYMETHYL-1,3-PROPANEDIOL)(2R-CIS)-(3-METHYLOXIRANYL)PHOSPHONATE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | ZAMBON S.p.A. (IT) | 1982-12-15 | — | — | EP | claimed |
| EP-0036138-A2 | Composition of matter for topical application comprising a bio-affecting agent and N,N-diethyl-m-toluamide | MERCK & CO. INC. (US) | 1981-09-23 | — | — | EP | claimed |
| EP-0026409-A1 | Combinations of active ingredients, pharmaceutical preparations, as well as their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-04-08 | — | — | EP | claimed |
| US-4143134-A | BACTERICIDES, ANTIBIOTIC POTENTIATORS | HOFFMANN-LA ROCHE INC. (US) | 1979-03-06 | — | — | US | claimed |
| US-3935309-A | CHLORAMPHENICOL | MERCK & CO., INC. (US) | 1976-01-27 | — | — | US | claimed |