Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28330270 | 0.97 | LMNA (0.55) | LMNAMAPTL3MBTL1CNR1CNR2 | |
| SCHEMBL4479542 | 0.94 | LMNA (0.58) | LMNAMAPTL3MBTL1CNR1CNR2 | |
| SCHEMBL28209598 | 0.93 | CCNB2 (0.52) | LMNAMAPTL3MBTL1CNR1CNR2 | |
| SCHEMBL9075084 | 0.89 | LTB4R (0.54) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL5163358 | 0.89 | CNR1 (0.50) | LMNAMAPTL3MBTL1CNR1CNR2 | |
| SCHEMBL5163351 | 0.88 | LMNA (0.56) | LMNAMAPTL3MBTL1CNR1CNR2 | |
| SCHEMBL29518968 | 0.88 | DRD2 (0.59) | LMNAMAPTL3MBTL1CNR1CNR2 | |
| SCHEMBL18917587 | 0.88 | DRD2 (0.59) | LMNAMAPTL3MBTL1CNR1CNR2 | |
| Bicarbonate SCHEMBL28775865 | 0.87 | DRD2 (0.58) | LMNAMAPTL3MBTL1CNR1CNR2 | |
| SCHEMBL4625163 | 0.86 | CNR1 (0.44) | LMNAMAPTL3MBTL1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106471043-A | The polysiloxanes of chromophore functionalization of UV activity and the copolymer being made from | 莫门蒂夫性能材料股份有限公司 | 2017-03-01 | — | — | CN | claimed |
| CN-110521290-B | Photosensitive resin composition, dry film using same, printed wiring board, and method for producing printed wiring board | 日立化成株式会社 | 2022-04-05 | — | — | CN | disclosed |
| US-9028728-B2 | Photochromic materials that include indeno-fused naphthopyrans | TRANSITIONS OPTICAL, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| WO-2013086248-A1 | PHOTOCHROMIC MATERIALS THAT INCLUDE INDENO-FUSED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 2013-06-13 | — | — | WO | disclosed |
| US-20120145973-A1 | Photochromic Materials That Include Indeno-Fused Naphthopyrans | TRANSITIONS OPTICAL INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120145973-A1 | Photochromic Materials That Include Indeno-Fused Naphthopyrans | NQO1, INTS6, IPO4 | LMNA 650/4885MAPT 2224/4885L3MBTL1 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.