SCHEMBL989913

SCHEMBL989913

Brc1cccc2ccc(-c3cccc4ccccc34)nc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.57
BACE1 P56817 1/20 0.49
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 3/20 0.44
HPGD P15428 3/20 0.44
KDM6B O15054 1/20 0.41
FTO Q9C0B1 1/20 0.41
NOS1 P29475 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 2/20 0.37
CYP2A6 P11509 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
NISCH Q9Y2I1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30414026 0.87 ALDH1A1 (0.50) ARALDH1A1KDM4EHPGDKDM6B
SCHEMBL14900756 0.87 ALDH1A1 (0.50) ARALDH1A1KDM4EHPGDKDM6B
SCHEMBL10032267 0.87 ALDH1A1 (0.50) ARALDH1A1KDM4EHPGDKDM6B
SCHEMBL10032295 0.85 ALDH1A1 (0.49) ARALDH1A1KDM4EHPGDKDM6B
SCHEMBL31339253 0.85 ALDH1A1 (0.43) ARALDH1A1KDM4EHPGDKDM6B
SCHEMBL28633687 0.85 ALDH1A1 (0.43) ARALDH1A1KDM4EHPGDKDM6B
SCHEMBL14884094 0.84 ALDH1A1 (0.47) ARALDH1A1KDM4EHPGDKDM6B
SCHEMBL10032245 0.81 ENPP3 (0.46) ARALDH1A1KDM4EHPGDKDM6B
SCHEMBL17931867 0.79 METAP2 (0.49) ARALDH1A1KDM4EHPGDKDM6B
SCHEMBL1645280 0.79 ALDH1A1 (0.48) ARALDH1A1KDM4EHPGDKDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2456794-A1 CATALYSTS BASED ON 2-ARYL-8-ANILINOQUINOLINE LIGANDS Equistar Chemicals, LP (US) 2012-05-30 EP disclosed
EP-2456795-A1 METHOD OF PREPARING NON-METALLOCENE CATALYSTS Equistar Chemicals, LP (US) 2012-05-30 EP disclosed
US-8153544-B2 Method for preparing non-metallocene catalysts EQUISTAR CHEMICALS, LP (US) 2012-04-10 US disclosed
US-8153544-B2 Method for preparing non-metallocene catalysts EQUISTAR CHEMICALS, LP (US) 2012-04-10 US disclosed
US-8153544-B2 Method for preparing non-metallocene catalysts EQUISTAR CHEMICALS, LP (US) 2012-04-10 US disclosed
US-20110021344-A1 Method for preparing non-metallocene ligands EQUISTAR CHEMICALS, LP 2011-01-27 US disclosed
WO-2011011039-A1 METHOD OF PREPARING NON-METALLOCENE CATALYSTS EQUISTAR CHEMICALS, LP (US) 2011-01-27 WO disclosed
WO-2011011039-A1 METHOD OF PREPARING NON-METALLOCENE CATALYSTS EQUISTAR CHEMICALS, LP (US) 2011-01-27 WO disclosed
US-20110021344-A1 Method for preparing non-metallocene ligands EQUISTAR CHEMICALS, LP 2011-01-27 US disclosed
US-20110021344-A1 Method for preparing non-metallocene ligands EQUISTAR CHEMICALS, LP 2011-01-27 US disclosed
WO-2011011041-A1 CATALYSTS BASED ON 2-ARYL-8-ANILINOQUINOLINE LIGANDS EQUISTAR CHEMICALS, LP (US) 2011-01-27 WO disclosed
WO-2011011041-A1 CATALYSTS BASED ON 2-ARYL-8-ANILINOQUINOLINE LIGANDS EQUISTAR CHEMICALS, LP (US) 2011-01-27 WO disclosed
US-7858718-B1 Catalysts based on 2-aryl-8-anilinoquinoline ligands EQUISTAR CHEMICALS, LP (US) 2010-12-28 US disclosed
US-7858718-B1 Catalysts based on 2-aryl-8-anilinoquinoline ligands EQUISTAR CHEMICALS, LP (US) 2010-12-28 US disclosed
US-7858718-B1 Catalysts based on 2-aryl-8-anilinoquinoline ligands EQUISTAR CHEMICALS, LP (US) 2010-12-28 US disclosed