Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10032267 | 0.87 | ALDH1A1 (0.50) | ALDH1A1HPGDTSHRHSD17B10NOS1 | |
| SCHEMBL14900756 | 0.87 | ALDH1A1 (0.50) | ALDH1A1HPGDTSHRHSD17B10NOS1 | |
| SCHEMBL30414026 | 0.87 | ALDH1A1 (0.50) | ALDH1A1HPGDTSHRHSD17B10NOS1 | |
| SCHEMBL10032295 | 0.85 | ALDH1A1 (0.49) | ALDH1A1HPGDTSHRHSD17B10NOS1 | |
| SCHEMBL14884094 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HPGDTSHRHSD17B10NOS1 | |
| SCHEMBL11366805 | 0.81 | NOS1 (0.54) | ALDH1A1HPGDHSD17B10NOS1KDM4E | |
| SCHEMBL10032245 | 0.81 | ENPP3 (0.46) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| SCHEMBL17931867 | 0.79 | METAP2 (0.49) | ALDH1A1HPGDCYP3A4TSHRHSD17B10 | |
| SCHEMBL12949735 | 0.79 | AR (0.63) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| SCHEMBL989913 | 0.79 | AR (0.57) | ALDH1A1HPGDTSHRHSD17B10NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102076816-B | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-10-22 | — | — | CN | disclosed |
| US-8597798-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2013-12-03 | — | — | US | disclosed |
| CN-102076816-A | Materials for organic electroluminescent devices | MERCK PATENT GMBH | 2011-05-25 | — | — | CN | disclosed |
| US-20110095281-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-04-28 | — | — | US | disclosed |
| US-20110095281-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-04-28 | — | — | US | disclosed |
| US-20110095281-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-04-28 | — | — | US | disclosed |
| WO-2010054731-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110095281-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SOD1, EPCAM, ICMT | ALDH1A1 283/4885HPGD 2548/4885CYP3A4 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.