Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329290 | 0.80 | — | — | |
| SCHEMBL7271410 | 0.75 | — | — | |
| SCHEMBL27856368 | 0.75 | — | — | |
| SCHEMBL7265440 | 0.69 | — | — | |
| SCHEMBL2639279 | 0.68 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL145757 | 0.67 | — | — | |
| SCHEMBL7573943 | 0.67 | GSR (0.35) | GSRALDH1A1HPGDHIF1A | |
| SCHEMBL18212306 | 0.67 | GSR (0.31) | GSRALDH1A1HPGDHIF1A | |
| Ammonia Solution, Strong SCHEMBL9793355 | 0.65 | — | — | |
| Ammonia Solution, Strong SCHEMBL11147056 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2665472-B1 | COMPOUNDS FOR TREATMENT OF HEART FAILURE | SOLVOTRIN INNOVATIONS LTD (IE) | 2022-07-06 | — | — | EP | disclosed |
| US-9566342-B2 | Compounds for treatment of heart failure | SOLVOTRIN INNOVATIONS LIMITED (IE) | 2017-02-14 | — | — | US | disclosed |
| US-20130338118-A1 | COMPOUNDS FOR TREATMENT OF HEART FAILURE | SOLVOTRIN INNOVATIONS LIMITED (IE) | 2013-12-19 | — | — | US | disclosed |
| EP-2665472-A1 | COMPOUNDS FOR TREATMENT OF HEART FAILURE | Solvotrin Innovations Limited (IE) | 2013-11-27 | — | — | EP | disclosed |
| WO-2012076667-A1 | COMPOUNDS FOR TREATMENT OF HEART FAILURE | SOLVOTRIN INNOVATIONS LIMITED (IE) | 2012-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130338118-A1 | COMPOUNDS FOR TREATMENT OF HEART FAILURE | MMP9, NOS2, MMP1 | GSR 556/4885ALDH1A1 2466/4885HPGD 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.