Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19725364 | 1.00 | GAA (0.58) | GAACYP1A2CYP2C9PKMCYP2C19 | |
| SCHEMBL11527529 | 0.92 | CYP1A2 (0.56) | GAACYP1A2CYP2C9PKMCYP2C19 | |
| SCHEMBL8363887 | 0.88 | CYP1A2 (0.77) | GAACYP1A2CYP2C9PKMCYP2C19 | |
| SCHEMBL473828 | 0.84 | CYP1A2 (0.78) | GAACYP1A2CYP2C9PKMCYP2C19 | |
| SCHEMBL127395 | 0.84 | CYP1A2 (0.78) | GAACYP1A2CYP2C9PKMCYP2C19 | |
| SCHEMBL43054 | 0.84 | CYP1A2 (0.78) | GAACYP1A2CYP2C9PKMCYP2C19 | |
| Benzene SCHEMBL27779381 | 0.84 | CYP1A2 (0.78) | GAACYP1A2CYP2C9PKMCYP2C19 | |
| Hydrochloric Acid SCHEMBL8691488 | 0.83 | CYP1A2 (0.75) | GAACYP1A2CYP2C9PKMCYP2C19 | |
| Hydrochloric Acid SCHEMBL1961683 | 0.83 | CYP1A2 (0.75) | GAACYP1A2CYP2C9PKMCYP2C19 | |
| SCHEMBL18205114 | 0.83 | CYP1A2 (0.75) | GAACYP1A2CYP2C9PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3235799-B1 | OXIME COMPOUND AND HERBICIDE | NISSAN CHEMICAL CORP (JP) | 2022-02-23 | — | — | EP | disclosed |
| US-20210230360-A1 | POLYCARBONATE AND PREPARATION METHOD THEREOF | LG CHEM, LTD. (KR) | 2021-07-29 | — | — | US | disclosed |
| US-11000033-B2 | Ketone or oxime compound, and herbicide | NISSAN CHEMICAL CORPORATION (JP) | 2021-05-11 | — | — | US | disclosed |
| US-20190053488-A1 | KETONE OR OXIME COMPOUND, AND HERBICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2019-02-21 | — | — | US | disclosed |
| US-20170347647-A1 | KETONE OR OXIME COMPOUND, AND HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-12-07 | — | — | US | disclosed |
| US-20170347647-A1 | KETONE OR OXIME COMPOUND, AND HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-12-07 | — | — | US | disclosed |
| EP-3235799-A1 | KETONE OR OXIME COMPOUND, AND HERBICIDE | Nissan Chemical Industries, Ltd. (JP) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016098899-A1 | KETONE OR OXIME COMPOUND, AND HERBICIDE | 日産化学工業株式会社 | 2016-06-23 | — | — | WO | disclosed |
| US-9255103-B2 | Substituted pyrazolo[1,5-a]pyrazines as mGluR5 receptor modulators | VANDERBILT UNIVERSITY (US) | 2016-02-09 | — | — | US | disclosed |
| US-8883766-B2 | Ion channel modulators and methods of use | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-11-11 | — | — | US | disclosed |
| US-20100179132-A1 | CARBOLINE DERIVATIVES USEFUL IN THE INHIBITION OF ANGIOGENESIS | PTC THERAPEUTICS, INC. | 2010-07-15 | — | — | US | disclosed |
| US-20100158858-A1 | ADMINISTRATION OF CARBOLINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISEASES | PTC THERAPEUTICS, INC. | 2010-06-24 | — | — | US | disclosed |
| US-7601840-B2 | Carboline derivatives useful in the inhibition of angiogenesis | PTC THERAPEUTICS, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-7332492-B2 | Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor | ASTRAZENECA AB (SE) | 2008-02-19 | — | — | US | disclosed |
| US-7332492-B2 | Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor | ASTRAZENECA AB (SE) | 2008-02-19 | — | — | US | disclosed |
| US-20070281962-A2 | Administering 1,2,3,6-tetrasubstituted pyrido[3,4-b]indoles to inhibit the 5'-untranslated region-dependent translation; anticarcinogenic agents; retinopathy, rheumatoid arthritis, psoriasis, atherosclerosis, obesity, macular degeneration | PCT THERAPEUTICS, INC. (US) | 2007-12-06 | — | — | US | disclosed |
| US-20070167476-A1 | Piperazine, [1,4]Diazepane, [1,4]Diazocane, and [1,5]Diazocane fused imidazo ring compounds | 3M INNOVATIVE PROPERTIES COMPANY | 2007-07-19 | — | — | US | disclosed |
| US-20070167476-A1 | Piperazine, [1,4]Diazepane, [1,4]Diazocane, and [1,5]Diazocane fused imidazo ring compounds | 3M INNOVATIVE PROPERTIES COMPANY | 2007-07-19 | — | — | US | disclosed |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
| US-4251622-A | CONTAINING A DYE, AN ARYL KETONE SENSITIZER, AND AN N-SUBSTITUTED POLYAMIDE OR A VINYL ACETATE POLYMER OF HIGH MOLECULAR WEIGHT | NIPPON PAINT CO., LTD. (JP) | 1981-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11000033-B2 | Ketone or oxime compound, and herbicide | OR10J3, CYP1B1, CBR3 | GAA 3870/4885CYP1A2 54/4885CYP2C9 20/4885 |
| US-20070167476-A1 | Piperazine, [1,4]Diazepane, [1,4]Diazocane, and [1,5]Diazocane fused imidazo ring compounds | IL4, IL2, IL5 | GAA 3312/4885CYP1A2 1717/4885CYP2C9 3950/4885 |
| US-20100158858-A1 | ADMINISTRATION OF CARBOLINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISEASES | RNMT, VEGFA, VHL | GAA 1188/4885CYP1A2 2360/4885CYP2C9 4426/4885 |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | GAA 4203/4885CYP1A2 1069/4885CYP2C9 3826/4885 |
| US-20190053488-A1 | KETONE OR OXIME COMPOUND, AND HERBICIDE | OR10J3, CYP1B1, CBR3 | GAA 3886/4885CYP1A2 57/4885CYP2C9 20/4885 |
| US-20070281962-A2 | Administering 1,2,3,6-tetrasubstituted pyrido[3,4-b]indoles to inhibit the 5'-untranslated region-dependent translation; anticarcinogenic agents; retinopathy, rheumatoid arthritis, psoriasis, atherosclerosis, obesity, macular degeneration | VEGFA, FLT4, MIF | GAA 4720/4885CYP1A2 3938/4885CYP2C9 4314/4885 |
| US-20100179132-A1 | CARBOLINE DERIVATIVES USEFUL IN THE INHIBITION OF ANGIOGENESIS | VEGFA, FLT4, PGF | GAA 4174/4885CYP1A2 2140/4885CYP2C9 4529/4885 |
| US-20170347647-A1 | KETONE OR OXIME COMPOUND, AND HERBICIDE | OR10J3, CYP1B1, CBR3 | GAA 3886/4885CYP1A2 57/4885CYP2C9 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.