Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994111 | 0.87 | LMNA (0.67) | LMNAGAAMAOBPOLBMAOA | |
| SCHEMBL18837908 | 0.85 | LMNA (0.64) | LMNAGAAMAOBPOLBMAOA | |
| SCHEMBL3565933 | 0.85 | LMNA (0.64) | LMNAGAAMAOBPOLBMAOA | |
| SCHEMBL12397417 | 0.82 | LMNA (0.60) | LMNAGAAMAOBPOLBMAOA | |
| SCHEMBL81547 | 0.81 | LMNA (1.00) | LMNAGAAMAOBPOLBMAOA | |
| SCHEMBL3320803 | 0.81 | GAA (0.59) | LMNAGAAMAOBPOLBMAOA | |
| SCHEMBL17228662 | 0.80 | KCNA2 (0.43) | LMNAGAAPOLBKMT2AALDH1A1 | |
| SCHEMBL16921602 | 0.79 | LMNA (0.68) | LMNAGAAMAOBPOLBMAOA | |
| SCHEMBL15452988 | 0.78 | GAA (0.44) | LMNAGAAMAOBPOLBMAOA | |
| SCHEMBL1785011 | 0.78 | LMNA (0.56) | LMNAGAAMAOBPOLBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005558-A | Compound, preparation method thereof and application thereof in cigarettes | 湖北中烟工业有限责任公司 | 2024-05-10 | — | — | CN | claimed |
| CN-116768792-B | Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof | 浙江工业大学 | 2024-10-18 | — | — | CN | disclosed |
| CN-118005558-A | Compound, preparation method thereof and application thereof in cigarettes | 湖北中烟工业有限责任公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-116768792-A | Cinnamamide-hydroxypyridone derivative, and preparation method and application thereof | 浙江工业大学 | 2023-09-19 | — | — | CN | disclosed |
| US-9938240-B2 | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX INC. (CA) | 2018-04-10 | — | — | US | disclosed |
| US-9938240-B2 | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX INC. (CA) | 2018-04-10 | — | — | US | disclosed |
| US-9938240-B2 | Fluorinated derivatives of 3-hydroxypyridin-4-ones | APOTEX INC. (CA) | 2018-04-10 | — | — | US | disclosed |
| US-20170247329-A1 | \"Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones\ | APOTEX TECHNOLOGIES INC. (CA) | 2017-08-31 | — | — | US | disclosed |
| US-20170247329-A1 | \"Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones\ | APOTEX TECHNOLOGIES INC. (CA) | 2017-08-31 | — | — | US | disclosed |
| US-20170247329-A1 | \"Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones\ | APOTEX TECHNOLOGIES INC. (CA) | 2017-08-31 | — | — | US | disclosed |
| US-5480894-A | 3-hydroxypyridin-4-one derivatives as chelating agents | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| EP-0644761-A1 | HYDROXYPYRIDIN-4-ONES FOR TREATMENT OF PARASITICAL INFECTIONS | BTG INTERNATIONAL LIMITED (GB) | 1995-03-29 | — | — | EP | disclosed |
| EP-0619808-A1 | 3-HYDROXYPYRIDIN-4-ONE DERIVATIVES AS CHELATING AGENTS | BTG INTERNATIONAL LIMITED (GB) | 1994-10-19 | — | — | EP | disclosed |
| WO-1994004498-A1 | 3-HYDROXYPYRIDIN-4-ONE DERIVATIVES AS CHELATING AGENTS | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1994-03-03 | — | — | WO | disclosed |
| WO-1993021919-A1 | HYDROXYPYRIDIN-4-ONES FOR TREATMENT OF PARASITICAL INFECTIONS | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1993-11-11 | — | — | WO | disclosed |
| US-5256676-A | 3-hydroxy-pyridin-4-ones useful for treating parasitic infections | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1993-10-26 | — | — | US | disclosed |
| WO-1992012131-A1 | 3-HYDROXYPYRIDIN-4-ONE DERIVATIVES AS PHARMACEUTICAL COMPOSITIONS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1992-07-23 | — | — | WO | disclosed |
| EP-0494754-A1 | 3-hydroxypyridin-4-one derivatives as pharmaceutical compositions | BRITISH TECHNOLOGY GROUP LTD (GB) | 1992-07-15 | — | — | EP | disclosed |
| US-4908371-A | Pharmaceuticals | CIBA-GEIGY CORPORATION (US) | 1990-03-13 | — | — | US | disclosed |
| EP-0316279-A2 | Ester derivatives of azacyclic hydroxycompounds | CIBA-GEIGY AG (CH) | 1989-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247329-A1 | \"Fluorinated Derivatives of 3-Hydroxypyridin-4-Ones\ | FH, FECH, FPGS | LMNA 2354/4885GAA 547/4885MAOB 513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.