Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SPR | P35270 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903594 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL1304161 | 0.83 | SMN1; SMN2 (0.41) | ALDH1A1KDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL1841864 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL23354462 | 0.82 | SMN1; SMN2 (0.41) | ALDH1A1LMNASMN1; SMN2RAB9ACYP1A2 | |
| Hydrochloric Acid SCHEMBL23354277 | 0.81 | SMN1; SMN2 (0.40) | ALDH1A1LMNASMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL23367091 | 0.79 | SMN1; SMN2 (0.40) | ALDH1A1KDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL23354517 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL433546 | 0.78 | RAB9A (0.46) | ALDH1A1LMNASMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL1302838 | 0.78 | SMN1; SMN2 (0.52) | ALDH1A1KDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL9901664 | 0.76 | GAA (0.48) | ALDH1A1KDM4ELMNASMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648518-A2 | PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2013-10-16 | — | — | EP | disclosed |
| US-20130253012-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2013-09-26 | — | — | US | disclosed |
| WO-2012076704-A2 | PYRAZOLE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2012-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130253012-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | RTN3, RRS1, RTF1 | ALDH1A1 3516/4885KDM4E 3482/4885LMNA 1667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.