Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902992 | 0.95 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTDRD2DRD4 | |
| SCHEMBL9902117 | 0.87 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTDRD2DRD4 | |
| SCHEMBL9902595 | 0.80 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2MAPTDRD2DRD4 | |
| SCHEMBL9902315 | 0.78 | EPHX1 (0.49) | ALDH1A1MAPTEPHX2GAA | |
| SCHEMBL9903230 | 0.77 | ALDH1A1 (0.54) | ALDH1A1EPHX2 | |
| SCHEMBL9901315 | 0.74 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTDRD2DRD4 | |
| SCHEMBL9903633 | 0.73 | DRD4 (0.39) | ALDH1A1SMN1; SMN2DRD4MEN1HTT | |
| SCHEMBL9901465 | 0.72 | MEN1 (0.43) | ALDH1A1SMN1; SMN2MAPTDRD2DRD4 | |
| SCHEMBL9903173 | 0.72 | EPHX1 (0.47) | ALDH1A1EPHX2KDM4EHTTCDK1 | |
| SCHEMBL9902657 | 0.70 | ALDH1A1 (0.52) | ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| CN-103347856-A | Multifunctional nitroxide derivatives and uses thereof | RADIKAL THERAPEUTICS INC | 2013-10-09 | — | — | CN | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |