Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901463 | 0.95 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2DRD2DRD4DRD3 | |
| SCHEMBL9902117 | 0.92 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2DRD2DRD4DRD3 | |
| SCHEMBL9901315 | 0.78 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2DRD2DRD4DRD3 | |
| SCHEMBL9902657 | 0.74 | ALDH1A1 (0.52) | ALDH1A1EPHX2 | |
| SCHEMBL9902595 | 0.73 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2DRD2DRD4DRD3 | |
| SCHEMBL9902315 | 0.71 | EPHX1 (0.49) | ALDH1A1MAPTRAB9APKMGAA | |
| SCHEMBL9902996 | 0.71 | MEN1 (0.46) | ALDH1A1SMN1; SMN2DRD2DRD4DRD3 | |
| SCHEMBL9903230 | 0.70 | ALDH1A1 (0.54) | ALDH1A1EPHX2 | |
| SCHEMBL9901557 | 0.70 | CTSL (0.46) | ALDH1A1SMN1; SMN2DRD2DRD4DRD3 | |
| SCHEMBL4017227 | 0.69 | DRD2 (0.65) | DRD2DRD4DRD3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| CN-103347856-A | Multifunctional nitroxide derivatives and uses thereof | RADIKAL THERAPEUTICS INC | 2013-10-09 | — | — | CN | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |