Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901315 | 0.94 | ALDH1A1 (0.50) | SMN1; SMN2EPHX2RAB9AEPHX1ALDH1A1 | |
| SCHEMBL9902315 | 0.86 | EPHX1 (0.49) | EPHX2RAB9AEPHX1ALDH1A1MAPT | |
| SCHEMBL9901557 | 0.85 | CTSL (0.46) | SMN1; SMN2EPHX2RAB9AEPHX1ALDH1A1 | |
| SCHEMBL9903230 | 0.84 | ALDH1A1 (0.54) | EPHX2ALDH1A1 | |
| SCHEMBL17271394 | 0.82 | ALDH1A1 (0.32) | SMN1; SMN2EPHX2RAB9AEPHX1ALDH1A1 | |
| SCHEMBL9901463 | 0.80 | ALDH1A1 (0.53) | SMN1; SMN2EPHX2ALDH1A1KMT2ALMNA | |
| SCHEMBL9903173 | 0.79 | EPHX1 (0.47) | EPHX2EPHX1ALDH1A1MAPK1TDP1 | |
| SCHEMBL9903633 | 0.78 | DRD4 (0.39) | SMN1; SMN2ALDH1A1KMT2AMEN1DRD4 | |
| SCHEMBL9902657 | 0.78 | ALDH1A1 (0.52) | EPHX2ALDH1A1 | |
| SCHEMBL16762665 | 0.76 | SMN1; SMN2 (0.59) | SMN1; SMN2EPHX2RAB9AEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |