Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902803 | 0.92 | GAA (0.41) | KDM4EGAAKMT2AKCNQ3KCNQ2 | |
| SCHEMBL9903032 | 0.88 | RECQL (0.37) | KDM4EGAAKMT2A | |
| SCHEMBL17271391 | 0.82 | KCNJ11 (0.33) | KDM4EGAAKMT2A | |
| SCHEMBL16994487 | 0.82 | KCNJ11 (0.33) | KDM4EGAAKMT2A | |
| SCHEMBL9905759 | 0.81 | KCNQ3 (0.33) | KDM4EGAAKMT2AKCNQ3KCNQ2 | |
| SCHEMBL9902283 | 0.78 | KDM4E (0.35) | KDM4EGAAKMT2A | |
| SCHEMBL9902043 | 0.77 | KDM4E (0.39) | KDM4EGAAKMT2A | |
| SCHEMBL9902954 | 0.76 | ALDH1A1 (0.41) | KDM4EGAAKMT2A | |
| SCHEMBL9901736 | 0.75 | KDM4E (0.35) | KDM4EGAAKMT2A | |
| SCHEMBL16994505 | 0.73 | KDM4E (0.37) | KDM4EGAAKMT2AKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |