Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902516 | 0.86 | GAA (0.40) | ALDH1A1EPHX2KMT2ARAB9ANPC1 | |
| SCHEMBL9903032 | 0.81 | RECQL (0.37) | ALDH1A1EPHX2KMT2ARAB9ANPC1 | |
| SCHEMBL16994501 | 0.81 | P2RX7 (0.39) | ALDH1A1EPHX2KMT2ARAB9ANPC1 | |
| SCHEMBL9902283 | 0.79 | KDM4E (0.35) | ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL9901731 | 0.76 | KDM4E (0.35) | KMT2AKDM4EGAA | |
| SCHEMBL9905735 | 0.75 | KDM4E (0.48) | ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL9902556 | 0.74 | GAA (0.38) | ALDH1A1KMT2AKDM4EGAASMN1; SMN2 | |
| SCHEMBL9902957 | 0.74 | KDM4E (0.37) | KMT2ARAB9AKDM4EGAASIGMAR1 | |
| SCHEMBL9902441 | 0.71 | P2RX7 (0.43) | ALDH1A1EPHX2KMT2ARAB9ANPC1 | |
| SCHEMBL16994507 | 0.71 | P2RX7 (0.43) | ALDH1A1EPHX2KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |