Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902470 | 0.92 | KDM4E (0.41) | KDM4EGAAKMT2ASLC6A2SLC6A4 | |
| SCHEMBL9902556 | 0.87 | GAA (0.38) | KDM4EGAAKMT2AGRM5ALDH1A1 | |
| SCHEMBL16994486 | 0.82 | KDM4E (0.32) | KDM4EGAAKMT2ASLC6A2SLC6A4 | |
| SCHEMBL9902713 | 0.81 | GRM5 (0.33) | KDM4EGAAKMT2ASLC6A2SLC6A4 | |
| SCHEMBL9902954 | 0.79 | ALDH1A1 (0.41) | KDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL9903032 | 0.78 | RECQL (0.37) | KDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL9901731 | 0.78 | KDM4E (0.35) | KDM4EGAAKMT2A | |
| SCHEMBL9902286 | 0.75 | KDM4E (0.35) | KDM4EGAAKMT2A | |
| SCHEMBL9902516 | 0.74 | GAA (0.40) | KDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL16994520 | 0.73 | KDM4E (0.37) | KDM4EGAAKMT2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |