Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901731 | 0.88 | KDM4E (0.35) | KDM4EGAAKMT2A | |
| SCHEMBL9902954 | 0.81 | ALDH1A1 (0.41) | NPC1RAB9AKDM4EGAAEPHX2 | |
| SCHEMBL16994489 | 0.80 | P2RX7 (0.38) | RECQLNPC1RAB9AEPHX1KDM4E | |
| SCHEMBL9901421 | 0.79 | EPHX2 (0.36) | RECQLNPC1RAB9AEPHX1GAA | |
| SCHEMBL9902283 | 0.78 | KDM4E (0.35) | KDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL9903261 | 0.78 | KDM4E (0.42) | NPC1RAB9AEPHX1KDM4EGAA | |
| SCHEMBL9902803 | 0.78 | GAA (0.41) | NPC1RAB9AKDM4EGAASMN1; SMN2 | |
| SCHEMBL9902043 | 0.78 | KDM4E (0.39) | KDM4EGAAKMT2A | |
| SCHEMBL9902516 | 0.76 | GAA (0.40) | NPC1RAB9AKDM4EGAAEPHX2 | |
| SCHEMBL9903243 | 0.76 | KDM4E (0.58) | EPHX1KDM4EGAAEPHX2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |