SCHEMBL990183

SCHEMBL990183

Cc1ccc(O[PH](=O)c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
L3MBTL1 Q9Y468 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
HPGD P15428 3/20 0.35
KMT2A Q03164 2/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
MEN1 O00255 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
TDP1 Q9NUW8 2/20 0.34
MRGPRX4 Q96LA9 1/20 0.34
LMNA P02545 2/20 0.33
TP53 P04637 1/20 0.33
S1PR4 O95977 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13189410 0.82 ACHE (0.40) ACHEL3MBTL1SMN1; SMN2HPGDKMT2A
SCHEMBL10978790 0.80 L3MBTL1 (0.41) ACHEL3MBTL1SMN1; SMN2HPGDKMT2A
SCHEMBL2817475 0.77 TP53 (0.40) ACHEL3MBTL1SMN1; SMN2HPGDKMT2A
SCHEMBL987477 0.74 HTT (0.41) ACHESMN1; SMN2TSHRCA1CA2
SCHEMBL31327825 0.73 TDP1 (0.42) ACHESMN1; SMN2HPGDKMT2AMEN1
SCHEMBL16398316 0.73 TDP1 (0.42) ACHESMN1; SMN2HPGDKMT2AMEN1
SCHEMBL28411952 0.71 SMN1; SMN2 (0.36) L3MBTL1SMN1; SMN2HPGDKMT2ATSHR
SCHEMBL562789 0.70 TDP1 (0.44) SMN1; SMN2KMT2AMEN1TDP1TP53
SCHEMBL968904 0.69 TSHR (0.38) ACHESMN1; SMN2HPGDKMT2ATSHR
SCHEMBL31666386 0.68 HTR1A (0.50) ACHEL3MBTL1SMN1; SMN2KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9822425-B2 Processes for recovering metals from aqueous solutions CYTEC TECHNOLOGY CORP. (US) 2017-11-21 US disclosed
US-8968698-B2 Processes for recovering metals from aqueous solutions CYTEC TECHNOLOGY CORP. (US) 2015-03-03 US disclosed
US-20140127095-A1 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2014-05-08 US disclosed
EP-2451985-A2 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS Cytec Technology Corporation (US) 2012-05-16 EP disclosed
WO-2011005736-A2 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2011-01-13 WO disclosed