SCHEMBL2817475

SCHEMBL2817475

Cc1ccc(O[PH](=O)O)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ACHE P22303 1/20 0.39
HPGD P15428 4/20 0.39
MRGPRX4 Q96LA9 1/20 0.39
LMNA P02545 2/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
NPC1 O15118 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15759862 0.84 HTT (0.47) TDP1SMN1; SMN2L3MBTL1MEN1KMT2A
SCHEMBL10978790 0.83 L3MBTL1 (0.41) TP53TDP1SMN1; SMN2L3MBTL1MEN1
SCHEMBL27377438 0.79 ACHE (0.39) SMN1; SMN2L3MBTL1ACHEHPGDLMNA
SCHEMBL990183 0.77 ACHE (0.36) TP53TDP1SMN1; SMN2L3MBTL1MEN1
SCHEMBL4451596 0.75 TSHR (0.41) TDP1SMN1; SMN2L3MBTL1MEN1KMT2A
SCHEMBL8952064 0.73 NCEH1 (0.36)
SCHEMBL9771530 0.72 L3MBTL1 (0.50) TP53TDP1SMN1; SMN2L3MBTL1MEN1
SCHEMBL28811047 0.72 PDK2 (0.37) TDP1L3MBTL1MEN1KMT2AHPGD
SCHEMBL10427454 0.72 TP53 (0.48) TP53TDP1SMN1; SMN2L3MBTL1MEN1
SCHEMBL37754 0.71 L3MBTL1 (0.53) TP53TDP1SMN1; SMN2L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10479809-B2 Method for producing alkenyl phosphorus compound MARUZEN PETROCHEMICAL CO., LTD. (JP) 2019-11-19 US disclosed
US-20190263847-A1 METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND MARUZEN PETROCHEMICAL CO., LTD. (JP) 2019-08-29 US disclosed
EP-3348561-A1 METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND Maruzen Petrochemical Co., Ltd. (JP) 2018-07-18 EP disclosed
EP-2421875-B1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES INVISTA TECHNOLOGIES SARL (CH) 2017-08-23 EP disclosed
EP-2421876-B1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES INVISTA Technologies S à r l (CH) 2016-07-27 EP disclosed
US-8772549-B2 Highly selective process for producing organodiphosphites INVISTA North America S.à r.l. (US) 2014-07-08 US disclosed
US-8604233-B2 Lubricant composition, magnetic recording medium, and novel polyether compound FUJIFILM CORPORATION (JP) 2013-12-10 US disclosed
US-8178711-B2 Method for the purification of triorganophosphites by treatment with a basic additive INVISTA NORTH AMERICA S.A R.L. (US) 2012-05-15 US disclosed
US-20100267991-A1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES INVISTA NORTH AMERICA S.A.R.L. (US) 2010-10-21 US disclosed
US-20100267990-A1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES INVISTA NORTH AMERICA S.A R.L. (US) 2010-10-21 US disclosed
US-7812171-B2 Black pigment, black pigment dispersion and black resin composition comprising the same FUJIFILM CORPORATION (JP) 2010-10-12 US disclosed
US-20100247971-A1 LUBRICANT COMPOSITION, MAGNETIC RECORDING MEDIUM, AND NOVEL POLYETHER COMPOUND FUJIFILM CORPORATION (JP) 2010-09-30 US disclosed
US-20100076212-A1 METHOD FOR THE PURIFICATION OF TRIORGANOPHOSPHITES BY TREATMENT WITH A BASIC ADDITIVE INVISTA NORTH AMERICA S.A R.L. (US) 2010-03-25 US disclosed
US-7629484-B2 Method for the purification of triorganophosphites by treatment with a basic additive INVISTA NORTH AMERICA S.A.R.L. (US) 2009-12-08 US disclosed
US-20080262237-A1 BLACK PIGMENT, BLACK PIGMENT DISPERSION AND BLACK RESIN COMPOSITION COMPRISING THE SAME FUJIFILM CORPORATION (JP) 2008-10-23 US disclosed
US-20070219386-A1 Method for the purification of triorganophosphites by treatment with a basic additive INVISTA NORTH AMERICA S.A R.L. (US) 2007-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219386-A1 Method for the purification of triorganophosphites by treatment with a basic additive HRH3, PHOSPHO1, HRH4 TP53 3729/4885TDP1 2668/4885SMN1; SMN2 4509/4885
US-20100247971-A1 LUBRICANT COMPOSITION, MAGNETIC RECORDING MEDIUM, AND NOVEL POLYETHER COMPOUND MUC1, NEFM, CA13 TP53 3873/4885TDP1 2436/4885SMN1; SMN2 210/4885
US-20100267990-A1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES AGPS, FDPS, DCPS TP53 3175/4885TDP1 1991/4885SMN1; SMN2 3456/4885
US-10479809-B2 Method for producing alkenyl phosphorus compound ORC3, OR10J3, ORAI3 TP53 3347/4885TDP1 3180/4885SMN1; SMN2 4182/4885
US-20100076212-A1 METHOD FOR THE PURIFICATION OF TRIORGANOPHOSPHITES BY TREATMENT WITH A BASIC ADDITIVE HRH3, PHOSPHO1, HRH4 TP53 3729/4885TDP1 2668/4885SMN1; SMN2 4509/4885
US-20080262237-A1 BLACK PIGMENT, BLACK PIGMENT DISPERSION AND BLACK RESIN COMPOSITION COMPRISING THE SAME DYNLL1, HNRNPL, AOX1 TP53 4066/4885TDP1 453/4885SMN1; SMN2 973/4885
US-20100267991-A1 HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES AGPS, FDPS, DCPS TP53 3175/4885TDP1 1991/4885SMN1; SMN2 3456/4885
US-20190263847-A1 METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND ORC3, OR10J3, ALK TP53 3581/4885TDP1 3486/4885SMN1; SMN2 4237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.