Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 11/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903412 | 0.88 | HTR6 (0.60) | HTR3AHTR6DRD2HTR7HTR2B | |
| SCHEMBL9903634 | 0.88 | HTR6 (0.50) | HTR3AHTR6DRD2HTR7HTR2B | |
| SCHEMBL9903167 | 0.86 | HTR6 (0.58) | HTR3AHTR6DRD2HTR7HTR2B | |
| SCHEMBL9902699 | 0.86 | HTR3A (0.48) | HTR3AHTR6DRD2HTR7HTR2B | |
| SCHEMBL9903178 | 0.85 | HTR3A (0.47) | HTR3AHTR6DRD2HTR7HTR2B | |
| SCHEMBL9903357 | 0.83 | HTR6 (0.59) | HTR3AHTR6DRD2HTR7HTR2B | |
| SCHEMBL9903832 | 0.82 | KHK (0.42) | HTR6DRD2HTR7HTR2BMAPT | |
| SCHEMBL9903853 | 0.80 | HTR6 (0.60) | HTR3AHTR6DRD2HTR7HTR2B | |
| SCHEMBL9903510 | 0.80 | HTR6 (0.60) | HTR3AHTR6DRD2HTR7HTR2B | |
| SCHEMBL9903672 | 0.80 | HTR6 (0.62) | HTR3AHTR6DRD2HTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1956004-B1 | Quinoline derivatives and their use as 5-HT6 ligands | GLAXO GROUP LTD (GB) | 2012-06-13 | — | — | EP | claimed |