Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.30 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28964059 | 0.85 | ALOX5 (0.37) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7675778 | 0.81 | ALOX5 (0.47) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9902253 | 0.80 | ALOX5 (0.46) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9903752 | 0.79 | ALOX5 (0.43) | ALOX5CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1371364 | 0.78 | THRB (0.41) | THRB | |
| SCHEMBL12391681 | 0.78 | THRB (0.38) | ALOX5THRBTSHRACACBHPGD | |
| SCHEMBL17844649 | 0.77 | THRB (0.41) | THRB | |
| Acetic Acid SCHEMBL28013205 | 0.76 | THRB (0.40) | THRBHPGD | |
| Propionic Acid SCHEMBL28013214 | 0.75 | THRB (0.39) | THRBHPGD | |
| SCHEMBL28013206 | 0.73 | HCAR2 (0.41) | THRBACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076288-A1 | COMPOSITE COMPRISING NANOPARTICLES AND METHOD OF MAKING NANOPARTICLES | UNIVERSITE DE LIEGE (BE) | 2012-06-14 | — | — | WO | disclosed |
| EP-2462898-A1 | Composite comprising nanoparticles and method for making nanoparticles | Université de Liège (BE) | 2012-06-13 | — | — | EP | disclosed |