Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | CFD | P00746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901736 | 0.85 | KDM4E (0.35) | KDM4EGAAKMT2A | |
| SCHEMBL9902957 | 0.81 | KDM4E (0.37) | KDM4EGAAKMT2ASIGMAR1 | |
| SCHEMBL9901424 | 0.79 | NOS1 (0.41) | NOS1NOS3SLC22A2SLC22A1SLC22A3 | |
| SCHEMBL9902286 | 0.79 | KDM4E (0.35) | KDM4EGAAKMT2A | |
| SCHEMBL9903262 | 0.79 | GRIN2D (0.44) | NOS1SLC22A2SLC22A1SLC22A3PLAU | |
| SCHEMBL9902519 | 0.77 | KDM4E (0.39) | NOS1NOS3KDM4EGAAKMT2A | |
| SCHEMBL9902809 | 0.76 | KDM4E (0.40) | KDM4EGAAKMT2A | |
| SCHEMBL9903032 | 0.75 | RECQL (0.37) | KDM4EGAAKMT2ARECQL | |
| SCHEMBL9902558 | 0.74 | KDM4E (0.37) | KDM4EGAAKMT2A | |
| SCHEMBL16994489 | 0.72 | P2RX7 (0.38) | KDM4EGAARORCKMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |