Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | IDH2 | P48735 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902286 | 0.87 | KDM4E (0.35) | KDM4EGAAKMT2A | |
| SCHEMBL9902519 | 0.79 | KDM4E (0.39) | KDM4EGAAKMT2A | |
| SCHEMBL9902476 | 0.79 | KDM4E (0.40) | KDM4EGAAKMT2A | |
| SCHEMBL9902556 | 0.75 | GAA (0.38) | KDM4EGAAKMT2AIDH1IDH2 | |
| SCHEMBL9902957 | 0.75 | KDM4E (0.37) | KDM4EGAAKMT2A | |
| SCHEMBL9903038 | 0.74 | NOS1 (0.38) | KDM4EGAAKMT2A | |
| SCHEMBL9901736 | 0.72 | KDM4E (0.35) | KDM4EGAAKMT2A | |
| SCHEMBL9902255 | 0.69 | KDM4E (0.50) | KDM4EGAAKMT2A | |
| SCHEMBL9902718 | 0.68 | KDM4E (0.30) | KDM4EGAAKMT2A | |
| SCHEMBL9902370 | 0.67 | SIGMAR1 (0.44) | KDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |