Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 6/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 2/20 | 0.34 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059378 | 0.80 | GNAI3 (0.33) | GNAO1GNAI3GNAI1 | |
| SCHEMBL9059667 | 0.70 | GNAO1 (0.38) | GNAO1GNAI3GNAI1ALOX5 | |
| SCHEMBL1043043 | 0.69 | GNAI3 (0.70) | GNAO1GNAI3GNAI1GUSBEBP | |
| SCHEMBL35895 | 0.69 | — | — | |
| SCHEMBL250855 | 0.69 | GNAI3 (0.70) | GNAO1GNAI3GNAI1GUSBEBP | |
| SCHEMBL18630997 | 0.67 | GNAI3 (0.74) | GNAO1GNAI3GNAI1GUSBEBP | |
| SCHEMBL7991671 | 0.67 | GNAI3 (0.74) | GNAO1GNAI3GNAI1GUSBEBP | |
| SCHEMBL7022103 | 0.67 | GNAI3 (0.74) | GNAO1GNAI3GNAI1GUSBEBP | |
| SCHEMBL1043024 | 0.67 | GNAI3 (0.74) | GNAO1GNAI3GNAI1GUSBEBP | |
| SCHEMBL1043420 | 0.67 | GNAI3 (0.74) | GNAO1GNAI3GNAI1GUSBEBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208959-A1 | METHOD FOR PRODUCING AN AQUEOUS POLYMER DISPERSION | BASF SE (DE) | 2012-08-16 | — | — | US | claimed |
| US-20120149840-A1 | PROCESS FOR PRODUCING AN AQUEOUS POLYMER DISPERSION | Univ. of Southern Mississippi Res. Foundation (US) | 2012-06-14 | — | — | US | claimed |
| US-9932315-B2 | Persistent carbene adducts and related methods | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170233349-A1 | PERSISTENT CARBENE ADDUCTS AND RELATED METHODS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-08-17 | — | — | US | disclosed |
| WO-2016022965-A1 | PERSISTENT CARBENE ADDUCTS AND RELATED METHODS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-02-11 | — | — | WO | disclosed |
| US-20120208959-A1 | METHOD FOR PRODUCING AN AQUEOUS POLYMER DISPERSION | BASF SE (DE) | 2012-08-16 | — | — | US | disclosed |
| US-20120149840-A1 | PROCESS FOR PRODUCING AN AQUEOUS POLYMER DISPERSION | Univ. of Southern Mississippi Res. Foundation (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149840-A1 | PROCESS FOR PRODUCING AN AQUEOUS POLYMER DISPERSION | PUF60, PARG, ACMSD | GNAO1 4040/4885GNAI3 4310/4885GNAI1 4111/4885 |
| US-20170233349-A1 | PERSISTENT CARBENE ADDUCTS AND RELATED METHODS | DNMT1, ALKBH2, DNMT3A | GNAO1 1632/4885GNAI3 1309/4885GNAI1 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.