Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989861 | 1.00 | CNR1 (0.57) | CNR1MAPTLMNAALOX12MEN1 | |
| Hydrochloric Acid SCHEMBL10770594 | 0.98 | MAPT (0.56) | CNR1MAPTLMNAALOX12MEN1 | |
| SCHEMBL989911 | 0.91 | TAAR1 (0.55) | CNR1MAPTLMNAALOX12MEN1 | |
| SCHEMBL989796 | 0.91 | TAAR1 (0.55) | CNR1MAPTLMNAALOX12MEN1 | |
| SCHEMBL991931 | 0.83 | TAAR1 (0.52) | MAPTLMNAGAAKMT2ATAAR1 | |
| SCHEMBL3989832 | 0.77 | KMT2A (0.46) | CNR1MAPTLMNAALOX12MEN1 | |
| SCHEMBL990693 | 0.73 | GAA (0.47) | CNR1LMNAMEN1GAAKMT2A | |
| SCHEMBL22834268 | 0.73 | CNR1 (1.00) | CNR1MAPTLMNAALOX12POLB | |
| SCHEMBL10501653 | 0.73 | DRD2 (0.58) | CNR1MAPTLMNAALOX12TAAR1 | |
| SCHEMBL2303570 | 0.73 | DRD2 (0.54) | CNR1MAPTLMNAALOX12TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274307-A1 | BRIDGED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Medivation Technologies, Inc. (US) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009120720-A1 | BRIDGED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES,INC. (US) | 2009-10-01 | — | — | WO | disclosed |