Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989911 | 0.91 | TAAR1 (0.55) | TAAR1MAPTGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL990628 | 0.83 | CNR1 (0.57) | TAAR1MAPTGAASMN1; SMN2LMNA | |
| SCHEMBL989861 | 0.83 | CNR1 (0.57) | TAAR1MAPTGAASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL10770594 | 0.81 | MAPT (0.56) | TAAR1MAPTGAASMN1; SMN2LMNA | |
| SCHEMBL7488316 | 0.79 | RAB9A (0.49) | TAAR1MAPTSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL12342243 | 0.78 | TAAR1 (0.59) | TAAR1GAAACHEL3MBTL1LMNA | |
| SCHEMBL13808352 | 0.77 | ACHE (0.68) | TAAR1GAASMN1; SMN2ACHELMNA | |
| SCHEMBL1120384 | 0.76 | GAA (0.49) | MAPTGAASMN1; SMN2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL119951 | 0.74 | GAA (0.48) | MAPTGAASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL934513 | 0.73 | GAA (0.46) | MAPTGAASMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274307-A1 | BRIDGED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Medivation Technologies, Inc. (US) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009120720-A1 | BRIDGED HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES,INC. (US) | 2009-10-01 | — | — | WO | disclosed |