SCHEMBL9908817

CC1C(O)[C@H](O[C@@H]2O[C@@H](OC=O)[C@@H](O[C@H]3OC(COS(=O)(=O)O)[C@@H](OC4CC(C(=O)O)[C@@H](O)[C@H](O)[C@@H]4O)[C@H](O)C3C)C(O)C2O)[C@H](COS(=O)(=O)O)O[C@@H]1OCCCCCN

nearest known ligand 0.40

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	BDNF	P23560	3/20	0.40

▸	PTN	P21246	2/20	0.40

▸	MDK	P21741	2/20	0.40

▸	F10	P00742	1/20	0.35

▸	IGF2R	P11717	2/20	0.34

▸	GJB2	P29033	5/20	0.33

▸	LGALS8	O00214	2/20	0.33

▸	LGALS3	P17931	2/20	0.33

▸	LGALS4	P56470	2/20	0.33

▸	VEGFA	P15692	5/20	0.32

▸	BMP2	P12643	3/20	0.32

▸	FGF1	P05230	3/20	0.32

▸	FGF2	P09038	3/20	0.32

▸	IFNG	P01579	2/20	0.32

▸	SFRP1	Q8N474	1/20	0.32

▸	HPSE	Q9Y251	4/20	0.31

▸	PF4	P02776	2/20	0.31

▸	CXCL12	P48061	2/20	0.31

▸	SHH	Q15465	2/20	0.31

▸	CCL2	P13500	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9908813	0.89	BDNF (0.50)	BDNFPTNMDKF10IGF2R
SCHEMBL9908818	0.87	BDNF (0.51)	BDNFPTNMDKF10IGF2R
SCHEMBL9908822	0.84	BDNF (0.50)	BDNFPTNMDKF10IGF2R
SCHEMBL9908821	0.84	BDNF (0.42)	BDNFPTNMDKF10GJB2
SCHEMBL17167541	0.73	BDNF (0.54)	BDNFPTNMDKF10LGALS8
SCHEMBL17167553	0.69	BDNF (0.55)	BDNFPTNMDKF10VEGFA
SCHEMBL14977909	0.69	F10 (0.41)	BDNFPTNMDKF10FGF1
SCHEMBL13773327	0.67	LGALS8 (0.63)	IGF2RGJB2LGALS8LGALS3LGALS4
SCHEMBL16263232	0.67	F10 (0.33)	F10FGF1
SCHEMBL16263233	0.67	F10 (0.35)	F10FGF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20120142560-A1	HEPARAN SULFATE SYNTHESIS	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US)	2012-06-07	—	—	US	disclosed