Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDNF | P23560 | 3/20 | 0.50 |
| ▸ | PTN | P21246 | 2/20 | 0.50 |
| ▸ | MDK | P21741 | 2/20 | 0.50 |
| ▸ | F10 | P00742 | 3/20 | 0.46 |
| ▸ | CXCL12 | P48061 | 3/20 | 0.44 |
| ▸ | CCL2 | P13500 | 2/20 | 0.44 |
| ▸ | CXCL10 | P02778 | 1/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.44 |
| ▸ | CCL5 | P13501 | 1/20 | 0.44 |
| ▸ | VEGFA | P15692 | 6/20 | 0.41 |
| ▸ | FGF2 | P09038 | 6/20 | 0.41 |
| ▸ | FGF1 | P05230 | 5/20 | 0.41 |
| ▸ | BMP2 | P12643 | 3/20 | 0.41 |
| ▸ | IFNG | P01579 | 2/20 | 0.41 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.41 |
| ▸ | SHH | Q15465 | 2/20 | 0.39 |
| ▸ | PF4 | P02776 | 2/20 | 0.39 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | BMP6 | P22004 | 1/20 | 0.39 |
| ▸ | CCL11 | P51671 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9908813 | 0.95 | BDNF (0.50) | BDNFPTNMDKF10CXCL12 | |
| SCHEMBL9908821 | 0.94 | BDNF (0.42) | BDNFPTNMDKF10CXCL12 | |
| SCHEMBL9908818 | 0.90 | BDNF (0.51) | BDNFPTNMDKF10CXCL12 | |
| SCHEMBL9908817 | 0.84 | BDNF (0.40) | BDNFPTNMDKF10CXCL12 | |
| SCHEMBL17167857 | 0.80 | F10 (0.53) | BDNFPTNMDKF10CXCL12 | |
| SCHEMBL30013150 | 0.78 | CXCL12 (0.56) | BDNFPTNMDKF10CXCL12 | |
| SCHEMBL17167539 | 0.76 | BDNF (0.51) | BDNFPTNMDKF10CXCL12 | |
| SCHEMBL16656905 | 0.76 | F10 (0.63) | BDNFPTNMDKF10CXCL12 | |
| SCHEMBL17167541 | 0.75 | BDNF (0.54) | BDNFPTNMDKF10CXCL12 | |
| SCHEMBL12360709 | 0.73 | F10 (0.62) | BDNFPTNMDKF10CXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160060365-A1 | HEPARAN SULFATE SYNTHESIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2016-03-03 | — | — | US | disclosed |
| US-20120142560-A1 | HEPARAN SULFATE SYNTHESIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060365-A1 | HEPARAN SULFATE SYNTHESIS | HPSE, STT3B, DDOST | BDNF 2146/4885PTN 335/4885MDK 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.