Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991 | 0.84 | TSHR (0.46) | ALDH1A1TSHRPOLBLMNAHSD17B10 | |
| SCHEMBL9424637 | 0.82 | POLB (0.44) | ALDH1A1TSHRPOLBLMNAHSD17B10 | |
| SCHEMBL25295616 | 0.80 | MGAM (0.33) | TSHRPOLBLMNAMGAMGAA | |
| SCHEMBL8563167 | 0.80 | ALDH1A1 (0.33) | ALDH1A1TSHRPOLB | |
| SCHEMBL15438716 | 0.80 | DGKA (0.35) | ALDH1A1TSHRPOLBLMNA | |
| SCHEMBL639641 | 0.78 | GAA (0.48) | ALDH1A1TSHRPOLBLMNAHSD17B10 | |
| SCHEMBL11042103 | 0.78 | POLB (0.34) | TSHRPOLBLMNA | |
| SCHEMBL2982463 | 0.77 | TDP1 (0.43) | ALDH1A1POLBLMNA | |
| SCHEMBL15438447 | 0.77 | LMNA (0.33) | LMNA | |
| SCHEMBL421908 | 0.77 | DGAT1 (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526642-B1 | TRITERPENE DERIVATIVE | SHIONOGI & CO (JP) | 1998-04-01 | — | — | EP | claimed |
| EP-0526642-A1 | TRITERPENE DERIVATIVE | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-02-10 | — | — | EP | claimed |
| EP-0526642-B1 | TRITERPENE DERIVATIVE | SHIONOGI & CO (JP) | 1998-04-01 | — | — | EP | disclosed |
| US-5248807-A | Endothelin antagonists, treatment of cardiovascular disorders | SHIONOGI & CO., LTD. (JP) | 1993-09-28 | — | — | US | disclosed |
| EP-0526642-A1 | TRITERPENE DERIVATIVE | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-02-10 | — | — | EP | disclosed |