SCHEMBL991059

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2969425	0.87	CHRNB2 (0.60)	CHRNB2CHRNB4CHRNA3CHRNA4HPGD
	SCHEMBL28627064	0.80	ALDH1A1 (0.46)	CHRNB2CHRNB4CHRNA3CHRNA4HPGD
	SCHEMBL28189112	0.79	TSHR (0.58)	CHRNB2CHRNB4CHRNA3CHRNA4HPGD
	SCHEMBL21538629	0.78	HPGD (0.68)	CHRNB2CHRNB4CHRNA3CHRNA4HPGD
	SCHEMBL2095210	0.78	NPC1 (0.67)	CHRNB2CHRNB4CHRNA3CHRNA4HPGD
	SCHEMBL3396666	0.77	NPC1 (0.56)	CHRNB2CHRNB4CHRNA3CHRNA4HPGD
	SCHEMBL698418	0.77	CHRNB2 (0.60)	CHRNB2CHRNB4CHRNA3CHRNA4HPGD
	SCHEMBL2095207	0.76	NPC1 (0.59)	CHRNB2CHRNB4CHRNA3CHRNA4HPGD
	SCHEMBL10897210	0.76	HPGD (0.65)	HPGDNPC1RAB9ACA12CA9
	SCHEMBL21995358	0.76	ALDH1A1 (0.42)	CHRNB2CHRNB4CHRNA3CHRNA4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.