Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627064 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1LMNAABCB1 | |
| SCHEMBL21995253 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPK1L3MBTL1ALOX5LMNA | |
| SCHEMBL22001301 | 0.82 | TSHR (0.48) | ALDH1A1MAPK1L3MBTL1LMNAABCB1 | |
| SCHEMBL25211503 | 0.80 | L3MBTL1 (0.48) | ALDH1A1MAPK1L3MBTL1ALOX5LMNA | |
| SCHEMBL16306384 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1ALOX5LTA4H | |
| SCHEMBL5577016 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1ALOX5LMNA | |
| SCHEMBL18668926 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPK1L3MBTL1LMNASLC15A1 | |
| Hydrochloric Acid SCHEMBL4310487 | 0.77 | LTA4H (0.53) | ALDH1A1MAPK1L3MBTL1ALOX5LMNA | |
| SCHEMBL390750 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1LTA4HABCB1 | |
| SCHEMBL21846519 | 0.76 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1ALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220106595-A1 | ANTIBACTERIAL ANTISENSE AGENTS | Pedanius Therapeutics Limited (GB) | 2022-04-07 | — | — | US | disclosed |
| EP-3887520-A1 | ANTIBACTERIAL ANTISENSE AGENTS | Pedanius Therapeutics Limited (GB) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020109792-A1 | ANTIBACTERIAL ANTISENSE AGENTS | Pedanius Therapeutics Limited (GB) | 2020-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220106595-A1 | ANTIBACTERIAL ANTISENSE AGENTS | SLC47A1, SLC47A2, ZFR | ALDH1A1 4038/4885MAPK1 3559/4885L3MBTL1 884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.