SCHEMBL9910884

SCHEMBL9910884

COP(=O)(O)OCC(N)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RY10 O00398 13/20 0.49
GPR34 Q9UPC5 7/20 0.49
GPR174 Q9BXC1 6/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28350789 0.83 P2RY10 (0.55) P2RY10GPR34GPR174
SCHEMBL1254622 0.82 P2RY10 (0.47) P2RY10GPR34GPR174
SCHEMBL21067424 0.81 P2RY10 (0.47) P2RY10GPR34GPR174
SCHEMBL13618513 0.81 P2RY10 (0.60) P2RY10GPR34GPR174
SCHEMBL19347656 0.81 P2RY10 (0.50) P2RY10GPR34GPR174
SCHEMBL17927564 0.81 P2RY10 (0.46) P2RY10GPR34GPR174
SCHEMBL18501623 0.81 P2RY10 (0.40) P2RY10GPR34GPR174
SCHEMBL26229066 0.81 P2RY10 (0.40) P2RY10GPR34GPR174
SCHEMBL22567208 0.80 S1PR1 (0.43) P2RY10GPR34GPR174
SCHEMBL12609430 0.80 P2RY10 (0.44) P2RY10GPR34GPR174

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136339-B2 Dihydroartemisinin diploid derivative, pharmaceutical composition thereof, and application SOUTHEAST UNIVERSITY (CN) 2021-10-05 US disclosed
US-20200040008-A1 DIHYDROARTEMISININ DIPLOID DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION SOUTHEAST UNIVERSITY (CN) 2020-02-06 US disclosed
US-8822670-B2 Method of synthesizing cDNA and method of synthesizing RNA chains, and nucleotide-immobilized carrier SUMITOMO BAKELITE COMPANY, LTD. (JP) 2014-09-02 US disclosed
US-8198020-B2 Contacting target cell or noncellular molecular entity with phagocytic marker and moiety that binds to a component that is present on or at surface of target cell or noncellular molecular entity, thereby increasing level or density of phagocytic marker on target cell; marker comprises phosphatidylserine POTENTIA PHARMACEUTICALS, INC. (US) 2012-06-12 US disclosed
US-20100016566-A1 Method of synthesizing cdna and method of synthesizing rna chains, and nucleotide-immobilized carrier KINOSHITA, KENJI (JP) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016566-A1 Method of synthesizing cdna and method of synthesizing rna chains, and nucleotide-immobilized carrier RNGTT, POLRMT, RNMT P2RY10 3742/4885GPR34 3449/4885GPR174 2639/4885
US-20200040008-A1 DIHYDROARTEMISININ DIPLOID DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION SSB, DHODH, QTRT1 P2RY10 1080/4885GPR34 3742/4885GPR174 3911/4885
US-11136339-B2 Dihydroartemisinin diploid derivative, pharmaceutical composition thereof, and application SSB, DHODH, QTRT1 P2RY10 1080/4885GPR34 3742/4885GPR174 3911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.