Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30301352 | 0.77 | CES1 (0.53) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL30301351 | 0.77 | CES1 (0.53) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL509365 | 0.76 | RAB9A (0.90) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL9911659 | 0.75 | DGAT1 (0.51) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL9911656 | 0.74 | SMN1; SMN2 (0.62) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL9911599 | 0.72 | RAB9A (0.95) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL4284108 | 0.72 | NPC1 (1.00) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL4280110 | 0.72 | RAB9A (0.80) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL4280117 | 0.71 | NPC1 (1.00) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL4291514 | 0.71 | NPC1 (1.00) | ALDH1A1MEN1KMT2ARAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140364467-A1 | CHEMICAL INDUCERS OF NEUROGENESIS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-12-11 | — | — | US | disclosed |
| US-8778940-B2 | Chemical inducers of neurogenesis | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130143885-A1 | CHEMICAL INDUCERS OF NEUROGENESIS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-06-06 | — | — | US | disclosed |
| US-8193225-B2 | Isoxazole amides, derivatives and methods of chemical induction of neurogenesis | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-06-05 | — | — | US | disclosed |
| US-8193225-B2 | Isoxazole amides, derivatives and methods of chemical induction of neurogenesis | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-06-05 | — | — | US | disclosed |
| US-20090036451-A1 | Chemical inducers of neurogenesis | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-02-05 | — | — | US | disclosed |
| US-20090036451-A1 | Chemical inducers of neurogenesis | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364467-A1 | CHEMICAL INDUCERS OF NEUROGENESIS | DCX, NES, GAP43 | ALDH1A1 415/4885MEN1 3223/4885KMT2A 1862/4885 |
| US-20090036451-A1 | Chemical inducers of neurogenesis | DCX, NES, GAP43 | ALDH1A1 415/4885MEN1 3223/4885KMT2A 1862/4885 |
| US-20130143885-A1 | CHEMICAL INDUCERS OF NEUROGENESIS | DCX, NES, GAP43 | ALDH1A1 415/4885MEN1 3223/4885KMT2A 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.