Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26290022 | 0.92 | KDM4E (0.45) | ALDH1A1KDM4EHPGDNPSR1GPR84 | |
| SCHEMBL13868624 | 0.91 | KDM4E (0.35) | ALDH1A1KDM4EHPGDNPSR1GPR84 | |
| SCHEMBL7488070 | 0.89 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDNPSR1GABRA1 | |
| SCHEMBL7473791 | 0.84 | NPC1 (0.33) | ALDH1A1HPGDGABRA1GABRG2GABRB3 | |
| SCHEMBL1847688 | 0.83 | GABRG2 (0.37) | ALDH1A1KDM4EHPGDNPSR1GABRG2 | |
| SCHEMBL5650444 | 0.83 | MAPT (0.38) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL891063 | 0.83 | LRP6 (0.33) | ALDH1A1KDM4ENPSR1GABRA1GABRG2 | |
| SCHEMBL7777302 | 0.82 | DHODH (0.37) | ALDH1A1KDM4EHPGDNPSR1GPR84 | |
| SCHEMBL5107478 | 0.82 | NR4A2 (0.37) | ALDH1A1KDM4EHPGDNPSR1GPR84 | |
| SCHEMBL5159693 | 0.81 | KDM4E (0.33) | ALDH1A1KDM4EHPGDNPSR1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560893-B1 | PHOTOCHROMIC COMPOSITIONS AND LIGHT TRANSMISSIBLE ARTICLES | ADVANCED POLYMERIK PTY LTD (AU) | 2012-06-06 | — | — | EP | disclosed |
| US-7807075-B2 | Photochromic compositions and light transmissible articles | ADVANCED POLYMERIK PTY LTD (AU) | 2010-10-05 | — | — | US | disclosed |
| US-7807075-B2 | Photochromic compositions and light transmissible articles | ADVANCED POLYMERIK PTY LTD (AU) | 2010-10-05 | — | — | US | disclosed |
| US-20080006798-A1 | Photochromic Compositions and Light Transmissible Articles | JAMES ROBINSON SPECIALITY INGREDIENTS LTD (GB) | 2008-01-10 | — | — | US | disclosed |
| US-20080006798-A1 | Photochromic Compositions and Light Transmissible Articles | JAMES ROBINSON SPECIALITY INGREDIENTS LTD (GB) | 2008-01-10 | — | — | US | disclosed |
| US-7247262-B2 | Photochromic compositions and light transmissible articles | POLYMERS AUSTRALIA PTY LTD. (AU) | 2007-07-24 | — | — | US | disclosed |
| US-7247262-B2 | Photochromic compositions and light transmissible articles | POLYMERS AUSTRALIA PTY LTD. (AU) | 2007-07-24 | — | — | US | disclosed |