SCHEMBL9912901

SCHEMBL9912901

O=[N+]([O-])c1ccc(N(c2ccc(-n3c4ccc(N(c5ccc([N+](=O)[O-])cc5)c5cccc6ccccc56)cc4c4cc(N(c5ccc([N+](=O)[O-])cc5)c5cccc6ccccc56)ccc43)cc2)c2cccc3ccccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.43
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
ATM Q13315 2/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
TLR9 Q9NR96 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MAPT P10636 3/20 0.40
LMNA P02545 1/20 0.40
ALOX5 P09917 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
MPI P34949 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
USP14 P54578 1/20 0.37
HTT P42858 1/20 0.37
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9912982 0.97 ALDH1A1 (0.49) ALDH1A1MEN1KMT2AATMCRHBP
SCHEMBL9912906 0.93 SIGMAR1 (0.41) ALDH1A1MEN1KMT2AATMCRHBP
SCHEMBL9912998 0.91 ALDH1A1 (0.43) ALDH1A1MEN1KMT2AATMCRHBP
SCHEMBL9912933 0.87 PDE4A (0.42) ALDH1A1MEN1KMT2AATMCRHBP
SCHEMBL9912966 0.86 SIGMAR1 (0.41) ALDH1A1MEN1KMT2AATMCRHBP
SCHEMBL9912864 0.85 L3MBTL1 (0.39) ATML3MBTL1SIGMAR1CNR2CNR1
SCHEMBL9912870 0.85 KDM4E (0.37) ALDH1A1ATML3MBTL1LMNAALOX5
SCHEMBL9912913 0.85 MEN1 (0.49) ALDH1A1MEN1KMT2AATMCRHBP
SCHEMBL9912894 0.84 ALDH1A1 (0.62) ALDH1A1MEN1KMT2AATMCRHBP
SCHEMBL9912972 0.84 L3MBTL1 (0.38) ALDH1A1ATML3MBTL1MAPTSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198801-B2 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed