Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912966 | 0.95 | SIGMAR1 (0.41) | PDE4APDE4BPDE4CPDE4DSIGMAR1 | |
| SCHEMBL9912906 | 0.94 | SIGMAR1 (0.41) | PDE4APDE4BPDE4CPDE4DSIGMAR1 | |
| SCHEMBL9912901 | 0.87 | ALDH1A1 (0.43) | PDE4APDE4BPDE4CPDE4DSIGMAR1 | |
| SCHEMBL9912934 | 0.87 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DSIGMAR1 | |
| SCHEMBL9912982 | 0.86 | ALDH1A1 (0.49) | PDE4APDE4BPDE4CPDE4DSIGMAR1 | |
| SCHEMBL9912919 | 0.85 | L3MBTL1 (0.38) | SIGMAR1MPIHTR7KDM4EATM | |
| SCHEMBL31528399 | 0.83 | MAPT (0.48) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL18980971 | 0.83 | KDM4E (0.46) | SIGMAR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13557391 | 0.81 | L3MBTL1 (0.42) | SIGMAR1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9912917 | 0.81 | SIGMAR1 (0.37) | SIGMAR1MEN1KMT2AMAPTMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198801-B2 | Materials for injecting or transporting holes and organic electroluminescence devices using the same | LG CHEM, LTD. (KR) | 2012-06-12 | — | — | US | disclosed |