SCHEMBL9912918

SCHEMBL9912918

Cc1ccc(N(c2cccc(-n3c4ccc(N(c5ccc(C)cc5)c5cccc6ccccc56)cc4c4cc(N(c5ccc(C)cc5)c5cccc6ccccc56)ccc43)c2)c2cccc3ccccc23)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.34
DHFR P00374 1/20 0.33
LMNA P02545 2/20 0.33
EGFR P00533 1/20 0.33
ERBB2 P04626 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PGR P06401 1/20 0.31
RORA P35398 1/20 0.31
RORC P51449 1/20 0.31
RORB Q92753 1/20 0.31
PMM2 O15305 1/20 0.31
MPI P34949 1/20 0.31
PHOSPHO1 Q8TCT1 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9912950 0.93 DHFR (0.33) SIGMAR1DHFREGFRERBB2CYP1A2
SCHEMBL9912917 0.93 SIGMAR1 (0.37) SIGMAR1DHFRLMNACYP1A2CYP2A6
SCHEMBL9912898 0.93 TP53 (0.35) SIGMAR1DHFRGAACYP1A2CYP2A6
SCHEMBL9912919 0.92 L3MBTL1 (0.38) SIGMAR1DHFRKDM4EATML3MBTL1
SCHEMBL9912978 0.92 APP (0.36) SIGMAR1DHFREGFRERBB2ALDH1A1
SCHEMBL13557391 0.89 L3MBTL1 (0.42) SIGMAR1DHFRLMNAALDH1A1GAA
SCHEMBL19660886 0.88 TSPO (0.36) LMNAEGFRERBB2ALDH1A1GAA
SCHEMBL9912910 0.88 SIGMAR1 (0.37) SIGMAR1DHFRLMNACYP1A2CYP2A6
SCHEMBL18980971 0.88 KDM4E (0.46) SIGMAR1DHFRALDH1A1GAAKDM4E
SCHEMBL1981141 0.87 L3MBTL1 (0.41) SIGMAR1DHFRLMNAALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198801-B2 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed
US-8198801-B2 Materials for injecting or transporting holes and organic electroluminescence devices using the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed