SCHEMBL991323

SCHEMBL991323

Nc1ncc(C(=O)O)c(O)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 5/20 0.44
GABRD O14764 5/20 0.44
GABRA1 P14867 5/20 0.44
GABRB1 P18505 5/20 0.44
GABRG2 P18507 5/20 0.44
GABRB3 P28472 5/20 0.44
GABRA5 P31644 5/20 0.44
GABRA3 P34903 5/20 0.44
GABRA2 P47869 5/20 0.44
GABRB2 P47870 5/20 0.44
GABRA4 P48169 5/20 0.44
GABRE P78334 5/20 0.44
GABRA6 Q16445 5/20 0.44
GABRG1 Q8N1C3 5/20 0.44
GABRG3 Q99928 5/20 0.44
GABRQ Q9UN88 5/20 0.44
KDM4E B2RXH2 5/20 0.43
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.38
ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16649308 0.83 HSP90AA1 (0.38) KDM4EKMT2AMEN1ALDH1A1MAPT
SCHEMBL8625804 0.81 GABRP (0.46) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL1540141 0.79 HPGD (0.59) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL14637332 0.79 KEAP1 (0.46) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL152156 0.78 HPGD (0.40) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL15530016 0.78 GABRP (0.43) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL10995891 0.77 TSHR (0.46) KDM4EALDH1A1MAPTHSP90AA1HPGD
SCHEMBL11240852 0.77 MEN1 (0.46) KDM4EKMT2AMEN1ALDH1A1THRB
Water SCHEMBL2745045 0.77 HPGD (0.39) GABRPGABRDGABRA1GABRB1GABRG2
Hydrochloric Acid SCHEMBL11591950 0.77 HPGD (0.39) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504571-A Right-embedded alcohol or fenchyl alcohol ester derivatives of 2-hydroxy nicotinic acid and pharmaceutical application thereof 苏州缘聚医药科技有限公司 2025-02-25 CN disclosed
EP-2632562-B1 METHODS FOR CAPTURING VIRUS LIKE PARTICLES FROM PLANTS USING EXPANDED BED CHROMATOGRAPHY PHILIP MORRIS PRODUCTS SA (CH) 2020-08-05 EP disclosed
US-20170282095-A1 Process For Isolation of Plasma or Serum Proteins THERAPURE BIOPHARMA INC. (CA) 2017-10-05 US disclosed
EP-2832726-B1 (2-HETEROARYLAMINO)SUCCINIC ACID DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2017-09-06 EP disclosed
US-9624260-B2 Process for isolation of plasma or serum proteins THERAPURE BIOPHARMA INC. (CA) 2017-04-18 US disclosed
EP-3127916-A1 ISOLATION OF PLASMA OR SERUM PROTEINS Therapure Biopharma Inc. (CA) 2017-02-08 EP disclosed
EP-2277912-B1 Isolation of plasma proteins THERAPURE BIOPHARMA INC (CA) 2016-09-28 EP disclosed
US-9428545-B2 Process for isolation of plasma or serum proteins THERAPURE BIOPHARMA INC. (CA) 2016-08-30 US disclosed
US-20160009757-A1 PROCESS FOR ISOLATION OF PLASMA OR SERUM PROTEINS THERAPURE BIOPHARMA INC. (CA) 2016-01-14 US disclosed
US-9206168-B2 (2-heteroarylamino) succinic acid derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-12-08 US disclosed
EP-1401289-A1 FRACTIONATION OF PROTEIN CONTAINING MIXTURES UPFRONT CHROMATOGRAPHY A/S (DK) 2004-03-31 EP disclosed
US-20040058937-A1 Heterocyclic mutilin esters and their use as antibacterials SMITHKLINE BEECHAM P.L.C. (GB) 2004-03-25 US disclosed
EP-1386660-A1 Isolation of proteins UPFRONT CHROMATOGRAPHY A/S (DK) 2004-02-04 EP disclosed
US-20030187227-A1 Isolation of immunoglobulins UPFRONT CHROMATOGRAPHY A/S 2003-10-02 US disclosed
EP-1309565-A1 HETEROCYCLIC MUTILIN ESTERS AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM PLC (GB) 2003-05-14 EP disclosed
US-6498236-B1 HYBRIDOMA CELL CULTURE SUPERNATANTS, ANIMAL PLASMA OR SERA, OR COLOSTRUM. THE METHOD INCLUDES THE USE OF A MINIMUM OF SALTS, SUCH AS LYOTROPIC SALTS, IN THE BINDING PROCESS AND PREFERABLY ALSO THE USE OF SMALL AMOUNTS OF ORGANIC SOLVENTS IN THE UPFRONT CHROMATOGRAPHY A/S (DK) 2002-12-24 US disclosed
WO-2002096215-A1 FRACTIONATION OF PROTEIN CONTAINING MIXTURES UPFRONT CHROMATOGRAPHY A/S (DK) 2002-12-05 WO disclosed
WO-2002012199-A1 HETEROCYCLIC MUTILIN ESTERS AND THEIR USE AS ANTIBACTERIALS SMITHKLINE BEECHAM P.L.C. (GB) 2002-02-14 WO disclosed
US-4447422-A Penicillins and compositions containing them BEECHAM GROUP P.1.C. (GB) 1984-05-08 US disclosed
EP-0067610-A1 Penicillins, a process for their preparation and compositions containing them BEECHAM GROUP PLC (GB) 1982-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058937-A1 Heterocyclic mutilin esters and their use as antibacterials MLN, MSH2, MRPL21 GABRP 1337/4885GABRD 1284/4885GABRA1 2442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.