Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912999 | 0.95 | ALDH1A1 (0.44) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL9913019 | 0.92 | NTRK1 (0.42) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL4843245 | 0.89 | KDM4E (0.47) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL9912909 | 0.89 | KDM4E (0.47) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL23029157 | 0.88 | KDM4E (0.40) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL21451754 | 0.88 | OXTR (0.42) | MAPTALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL9913016 | 0.88 | L3MBTL1 (0.45) | MAPTALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL9912990 | 0.88 | L3MBTL1 (0.45) | MAPTALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL9913018 | 0.88 | L3MBTL1 (0.45) | MAPTALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL9913021 | 0.86 | MTNR1A (0.42) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198801-B2 | Materials for injecting or transporting holes and organic electroluminescence devices using the same | LG CHEM, LTD. (KR) | 2012-06-12 | — | — | US | disclosed |