Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692734 | 0.92 | LMNA (0.47) | NR1H4LMNAHTTPRKAB2PRKAG1 | |
| SCHEMBL21016381 | 0.88 | EPHX2 (0.51) | EPHX2NR1H4LMNAHTTESRRG | |
| SCHEMBL1507761 | 0.85 | HPGD (0.49) | LMNAHTTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1508030 | 0.85 | POLB (0.50) | LMNAHTTMAPTSIRT2POLB | |
| SCHEMBL1508016 | 0.84 | POLB (0.50) | LMNAHTTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1507990 | 0.81 | MAPT (0.53) | EPHX2NR1H4LMNAELANEMAPT | |
| SCHEMBL1507969 | 0.79 | NPC1 (0.40) | LMNAHTTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL17865779 | 0.78 | LMNA (0.58) | LMNAHTTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL14846585 | 0.78 | ROCK2 (0.54) | NR1H4LMNAHTTPRKAB2PRKAG1 | |
| SCHEMBL10169241 | 0.78 | PRKAB2 (0.52) | LMNAHTTESRRGPRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198460-B2 | Process for preparation of letrozole and its intermediates | FRESENIUS KABI ONCOLOGY LTD. (IN) | 2012-06-12 | — | — | US | disclosed |
| US-20100234617-A1 | PROCESS FOR PREPARATION OF LETROZOLE AND ITS INTERMEDIATES | FRESENIUS KABI ONCOLOGY LTD. (IN) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234617-A1 | PROCESS FOR PREPARATION OF LETROZOLE AND ITS INTERMEDIATES | CYP19A1, CYP4B1, CYP3A4 | EPHX2 2630/4885NR1H4 939/4885LMNA 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.