Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915116 | 0.86 | NAAA (0.50) | ALDH1A1GAASMN1; SMN2NAAACES1 | |
| SCHEMBL11568737 | 0.84 | ALDH1A1 (0.55) | ALDH1A1GAASMN1; SMN2NAAACES1 | |
| SCHEMBL9915105 | 0.80 | NPC1 (0.49) | GAASMN1; SMN2CES1CES2ALOX15 | |
| SCHEMBL27515367 | 0.80 | ALOX15 (0.56) | ALDH1A1GAASMN1; SMN2CES1CES2 | |
| SCHEMBL9915084 | 0.79 | HDAC3 (0.50) | ALDH1A1GAASMN1; SMN2CES1CES2 | |
| SCHEMBL11572800 | 0.77 | HDAC1 (0.49) | ALDH1A1GAASMN1; SMN2NAAAALOX15 | |
| SCHEMBL10445377 | 0.77 | GAA (0.50) | ALDH1A1GAASMN1; SMN2NAAACES1 | |
| SCHEMBL9274738 | 0.76 | ALOX15 (0.52) | ALDH1A1GAASMN1; SMN2CES1ALOX15 | |
| SCHEMBL9915104 | 0.76 | POLB (0.53) | GAASMN1; SMN2NAAAALOX15HDAC3 | |
| SCHEMBL11570689 | 0.75 | SMN1; SMN2 (0.57) | ALDH1A1GAASMN1; SMN2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096504-B2 | Controlled chemical release of hydrogen sulfide | WASHINGTON STATE UNIVERSITY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130253051-A1 | CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE | WASHINGTON STATE UNIVERSITY (US) | 2013-09-26 | — | — | US | disclosed |
| WO-2012075242-A2 | CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130253051-A1 | CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE | GSR, AR, GRHPR | ALDH1A1 2368/4885GAA 3647/4885SMN1; SMN2 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.