Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP9 | P55211 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11172245 | 0.87 | CES1 (0.57) | CES1BCHEMAOAALDH1A1KDM4E | |
| SCHEMBL11143500 | 0.82 | CYP1A2 (0.61) | CES1BCHEMAOAALDH1A1KDM4E | |
| SCHEMBL4668953 | 0.80 | MAOA (0.56) | CES1BCHEMAOAALDH1A1KDM4E | |
| SCHEMBL569873 | 0.80 | — | — | |
| SCHEMBL31070117 | 0.80 | — | — | |
| SCHEMBL8035811 | 0.80 | CES1 (0.73) | CES1BCHEMAOAALDH1A1KDM4E | |
| SCHEMBL3788168 | 0.80 | CES1 (0.58) | CES1BCHEMAOAMAOBCYP2A6 | |
| SCHEMBL976344 | 0.76 | CES1 (0.67) | CES1BCHEMAOAALDH1A1KDM4E | |
| SCHEMBL3638469 | 0.76 | CES1 (0.67) | CES1BCHEMAOAALDH1A1KDM4E | |
| SCHEMBL18032688 | 0.76 | CES1 (0.67) | CES1BCHEMAOAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160130560-A1 | METHODS FOR IN VITRO MATURATION OF OVARIAN FOLLICLES | LIU KUI (SE) | 2016-05-12 | — | — | US | disclosed |
| US-9259438-B2 | Methods for in vitro maturation of ovarian follicles | LIU KUI (SE) | 2016-02-16 | — | — | US | disclosed |
| US-20140213609-A1 | PROMOTING AXON RENEGERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2014-07-31 | — | — | US | disclosed |
| US-8728756-B2 | Promoting axon regeneration in the adult CNS through control of protein translation | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2014-05-20 | — | — | US | disclosed |
| US-20130123228-A1 | PROMOTING AXON REGENERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2013-05-16 | — | — | US | disclosed |
| US-8367352-B2 | Promoting axon regeneration in the adult CNS through control of protein translation | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2013-02-05 | — | — | US | disclosed |
| US-20120210523-A1 | COMPOSITION COMPRISING AN ACID DYE OF INDIGOID TYPE AND DYEING METHOD | L'OREAL (FR) | 2012-08-23 | — | — | US | disclosed |
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-20110015169-A1 | METHODS FOR IN VITRO MATURATION OF OVARIAN FOLLICLES | LIU KUI | 2011-01-20 | — | — | US | disclosed |
| US-20110002877-A1 | PTEN Inhibitors Treat Neutropenia-Associated Pneumonia | CHILDREN'S MEDICAL CENTER CORPORATION | 2011-01-06 | — | — | US | disclosed |
| EP-2236488-A1 | Materials, methods and uses for photochemical generation of acids and/or radical species | The Arizona Board of Regents on behalf of the University of Arizona (US) | 2010-10-06 | — | — | EP | disclosed |
| US-20090305333-A1 | Promoting Axon Regeneration in the Adult CNS through Control of Protein Translation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-12-10 | — | — | US | disclosed |
| US-20090192173-A1 | ANTI-TUBERCULAR DRUGS: COMPOSITIONS AND METHODS | SEQUELLA, INC. | 2009-07-30 | — | — | US | disclosed |
| US-20090092766-A1 | GRAFT PATTERN FORMING METHOD AND CONDUCTIVE PATTERN FORMING METHOD | FUJIFILM CORPORATION (JP) | 2009-04-09 | — | — | US | disclosed |
| US-20080283804-A1 | include a bridge of pi-conjugated bonds connecting electron donating or accepting groups; electronically excited upon absorption lead to formation of Lewis acidic species, Lewis basic species, radical species or ionic species; chromogens use in engineering, biological, and medicinal field | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2008-11-20 | — | — | US | disclosed |
| US-20070203098-A1 | Pten Inhibitors | SEMAFORE PHARMACEUTICALS, INC. (US) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120210523-A1 | COMPOSITION COMPRISING AN ACID DYE OF INDIGOID TYPE AND DYEING METHOD | KRT18, H1-5, IK | CES1 3911/4885BCHE 4435/4885MAOA 754/4885 |
| US-20110002877-A1 | PTEN Inhibitors Treat Neutropenia-Associated Pneumonia | CSF3R, CSF1R, ATM | CES1 4535/4885BCHE 4289/4885MAOA 4736/4885 |
| US-20110015169-A1 | METHODS FOR IN VITRO MATURATION OF OVARIAN FOLLICLES | PTEN, POF1B, PTP4A2 | CES1 4101/4885BCHE 4666/4885MAOA 1044/4885 |
| US-20090192173-A1 | ANTI-TUBERCULAR DRUGS: COMPOSITIONS AND METHODS | RIF1, TERT, ELL | CES1 3580/4885BCHE 442/4885MAOA 1983/4885 |
| US-20130123228-A1 | PROMOTING AXON REGENERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | GAP43, BDNF, DCX | CES1 4254/4885BCHE 2056/4885MAOA 3695/4885 |
| US-20070203098-A1 | Pten Inhibitors | PTEN, MTMR1, PTPRJ | CES1 1635/4885BCHE 4554/4885MAOA 3933/4885 |
| US-20140213609-A1 | PROMOTING AXON RENEGERATION IN THE ADULT CNS THROUGH CONTROL OF PROTEIN TRANSLATION | GAP43, DCX, BDNF | CES1 4367/4885BCHE 1869/4885MAOA 3827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.