SCHEMBL9916561

SCHEMBL9916561

CC1(C)c2ccccc2-c2ccc(-c3ccc(N(c4ccc(-c5ccc6oc7ccccc7c6c5)cc4)c4ccc5c(c4)C(C)(C)c4ccccc4-5)cc3)cc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALK Q9UM73 2/20 0.34
PLA2G2A P14555 1/20 0.33
PLA2G4A P47712 1/20 0.33
PGR P06401 1/20 0.33
PDK2 Q15119 7/20 0.33
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
TNKS O95271 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9916889 1.00 HSP90AA1 (0.36) HSP90AA1HSP90AB1KDM4EMEN1NPC1
SCHEMBL9916428 0.99 HSP90AA1 (0.37) HSP90AA1HSP90AB1KDM4EMEN1NPC1
SCHEMBL9916685 0.99 HSP90AA1 (0.37) HSP90AA1HSP90AB1KDM4EMEN1NPC1
SCHEMBL9916916 0.99 HSP90AA1 (0.37) HSP90AA1HSP90AB1KDM4EMEN1NPC1
SCHEMBL6373571 0.99 HSP90AA1 (0.37) HSP90AA1HSP90AB1KDM4EMEN1NPC1
SCHEMBL9916914 0.99 HSP90AA1 (0.37) HSP90AA1HSP90AB1KDM4EMEN1NPC1
SCHEMBL6374361 0.99 HSP90AA1 (0.37) HSP90AA1HSP90AB1KDM4EMEN1NPC1
SCHEMBL9916531 0.98 PLA2G2A (0.37) HSP90AA1HSP90AB1KDM4EMEN1NPC1
SCHEMBL9916309 0.98 PLA2G2A (0.37) HSP90AA1HSP90AB1KDM4EMEN1NPC1
SCHEMBL17126743 0.98 HSP90AA1 (0.35) HSP90AA1HSP90AB1KDM4EMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11335858-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2022-05-17 US disclosed
US-11056652-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2021-07-06 US disclosed
US-11024815-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-06-01 US disclosed
EP-3693437-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES Merck Patent GmbH (DE) 2020-08-12 EP disclosed
EP-3345984-B1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-03-04 EP disclosed
US-20190288209-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-09-19 US disclosed
US-20190288208-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-09-19 US disclosed
US-10396297-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2019-08-27 US disclosed
EP-3254317-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-07-31 EP disclosed
US-10355218-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2019-07-16 US disclosed
US-20160301005-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-10-13 US disclosed
WO-2016124304-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2016-08-11 WO disclosed
US-20160064669-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-03-03 US disclosed
US-20160064669-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-03-03 US disclosed
US-9260390-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-16 US disclosed
US-9260390-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-16 US disclosed
WO-2015082056-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-06-11 WO disclosed
EP-2468725-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME Idemitsu Kosan Co., Ltd. (JP) 2012-06-27 EP disclosed
US-20120146014-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-14 US disclosed
US-20120146014-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10396297-B2 Materials for electronic devices DDT, PNMT, COMT HSP90AA1 4358/4885HSP90AB1 4643/4885KDM4E 3105/4885
US-11056652-B2 Compounds and organic electronic devices ETV6, AFF2, CYP2C19 HSP90AA1 4509/4885HSP90AB1 4691/4885KDM4E 2144/4885
US-20190288208-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME RER1, NR4A1, REL HSP90AA1 4153/4885HSP90AB1 4625/4885KDM4E 1053/4885
US-11024815-B2 Metal complexes EXOC4, EXOC3, TIMCC HSP90AA1 4412/4885HSP90AB1 4590/4885KDM4E 3894/4885
US-10355218-B2 Aromatic amine derivatives and organic electroluminescent elements using same RER1, NR4A1, REL HSP90AA1 4172/4885HSP90AB1 4636/4885KDM4E 1061/4885
US-20190288209-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, AFF2, CYP2C19 HSP90AA1 4509/4885HSP90AB1 4691/4885KDM4E 2144/4885
US-20120146014-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME PNMT, TYR, AOC2 HSP90AA1 4687/4885HSP90AB1 4855/4885KDM4E 141/4885
US-20160064669-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME PNMT, TYR, AOC2 HSP90AA1 4687/4885HSP90AB1 4855/4885KDM4E 141/4885
US-11335858-B2 Aromatic amine derivatives and organic electroluminescent elements using same RER1, NR4A1, REL HSP90AA1 4153/4885HSP90AB1 4625/4885KDM4E 1053/4885
US-20160301005-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, AFF2, CYP2C19 HSP90AA1 4509/4885HSP90AB1 4691/4885KDM4E 2144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.