Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13658622 | 0.87 | L3MBTL1 (0.47) | PARP14ALOX5GPR3PRKDCMAPT | |
| SCHEMBL16437714 | 0.86 | PARP14 (0.55) | PARP14ALOX5GPR3PRKDCMAPT | |
| SCHEMBL16553319 | 0.85 | ALOX5 (0.61) | PARP14ALOX5GPR3PRKDCMAPT | |
| SCHEMBL21742792 | 0.84 | PARP14 (0.54) | PARP14ALOX5GPR3PRKDCMAPT | |
| SCHEMBL22104930 | 0.84 | PARP14 (0.56) | PARP14ALOX5GPR3PRKDCMAPT | |
| SCHEMBL429382 | 0.83 | ALOX5 (0.59) | PARP14ALOX5GPR3PRKDCMAPT | |
| SCHEMBL431845 | 0.83 | ALOX5 (0.59) | PARP14ALOX5GPR3PRKDCMAPT | |
| SCHEMBL10018846 | 0.83 | ALOX5 (0.59) | PARP14ALOX5GPR3PRKDCMAPT | |
| SCHEMBL12996528 | 0.83 | ALOX5 (0.59) | PARP14ALOX5GPR3PRKDCMAPT | |
| SCHEMBL18518758 | 0.82 | PARP14 (0.49) | PARP14ALOX5GPR3PRKDCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-11-23 | — | — | US | disclosed |
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-11-23 | — | — | US | disclosed |
| WO-2021214348-A2 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-10-28 | — | — | WO | disclosed |
| US-9614160-B2 | Aromatic amine derivatives and organic electroluminescent elements using same | IDEMITSU KOSAN CO., LTD. (JP) | 2017-04-04 | — | — | US | disclosed |
| US-20160064669-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2016-03-03 | — | — | US | disclosed |
| US-9260390-B2 | Aromatic amine derivatives and organic electroluminescent elements using same | IDEMITSU KOSAN CO., LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20120146014-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373941-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP2E1, GPX1, ERCC1 | PARP14 3423/4885ALOX5 2648/4885CYP1A2 46/4885 |
| US-20120146014-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | PNMT, TYR, AOC2 | PARP14 2222/4885ALOX5 1407/4885CYP1A2 1383/4885 |
| US-20160064669-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | PNMT, TYR, AOC2 | PARP14 2222/4885ALOX5 1407/4885CYP1A2 1383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.