Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9917236 | 0.97 | MAOB (0.41) | MAOBPGRTNKSPARP1TNKS2 | |
| SCHEMBL9917145 | 0.92 | PGR (0.40) | MAOBPGRTNKSPARP1TNKS2 | |
| SCHEMBL9917237 | 0.90 | KDM4E (0.41) | MAOBPGRTNKSPARP1TNKS2 | |
| SCHEMBL20026475 | 0.89 | AHR (0.41) | MAOBPGRMAOAAHRMEN1 | |
| SCHEMBL19011152 | 0.87 | PGR (0.46) | MAOBPGRTNKSPARP1TNKS2 | |
| SCHEMBL17523465 | 0.87 | PDK2 (0.41) | MAOBPGRTNKSPARP1TNKS2 | |
| SCHEMBL17051479 | 0.86 | MAOB (0.35) | MAOBPGRTNKSPARP1TNKS2 | |
| SCHEMBL19011149 | 0.86 | PGR (0.48) | MAOBPGRTNKSPARP1TNKS2 | |
| SCHEMBL19152295 | 0.85 | TNKS (0.39) | MAOBPGRTNKSMAOAAHR | |
| SCHEMBL9917234 | 0.85 | MAOB (0.39) | MAOBPGRTNKSPARP1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-02-20 | — | — | US | disclosed |
| US-20170162790-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2017-06-08 | — | — | US | disclosed |
| US-9614160-B2 | Aromatic amine derivatives and organic electroluminescent elements using same | IDEMITSU KOSAN CO., LTD. (JP) | 2017-04-04 | — | — | US | disclosed |
| US-20160064669-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2016-03-03 | — | — | US | disclosed |
| US-9260390-B2 | Aromatic amine derivatives and organic electroluminescent elements using same | IDEMITSU KOSAN CO., LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| EP-2468725-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |
| US-20120146014-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170162790-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | RER1, NR4A1, REL | MAOB 331/4885PGR 930/4885TNKS 4121/4885 |
| US-20120146014-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | PNMT, TYR, AOC2 | MAOB 208/4885PGR 2859/4885TNKS 3400/4885 |
| US-20200055822-A1 | MATERIALS FOR ORGANIC ELECTRONIC DEVICES | PNMT, DDT, TYR | MAOB 19/4885PGR 1113/4885TNKS 1748/4885 |
| US-20160064669-A1 | AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME | PNMT, TYR, AOC2 | MAOB 208/4885PGR 2859/4885TNKS 3400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.